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==PRECURSOR OF THE W11F MUTANT GLYCOSYLASPARAGINASE FROM FLAVOBACTERIUM MENINGOSEPTICUM==
==PRECURSOR OF THE W11F MUTANT GLYCOSYLASPARAGINASE FROM FLAVOBACTERIUM MENINGOSEPTICUM==
<StructureSection load='9gaf' size='340' side='right' caption='[[9gaf]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='9gaf' size='340' side='right'caption='[[9gaf]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[9gaf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_13253 Atcc 13253]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9GAF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=9GAF FirstGlance]. <br>
<table><tr><td colspan='2'>[[9gaf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Elizabethkingia_meningoseptica Elizabethkingia meningoseptica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9GAF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9GAF FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLY:GLYCINE'>GLY</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.26 3.5.1.26] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLY:GLYCINE'>GLY</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=9gaf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9gaf OCA], [http://pdbe.org/9gaf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=9gaf RCSB], [http://www.ebi.ac.uk/pdbsum/9gaf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=9gaf ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9gaf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9gaf OCA], [https://pdbe.org/9gaf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9gaf RCSB], [https://www.ebi.ac.uk/pdbsum/9gaf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9gaf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ASPG_ELIMR ASPG_ELIMR]] Cleaves the GlcNAc-Asn bond which joins oligosaccharides to the peptide of asparagine-linked glycoproteins. Requires that the glycosylated asparagine moiety is not substituted on its N-(R1) and C- (R2) terminus.  
[https://www.uniprot.org/uniprot/ASPG_ELIMR ASPG_ELIMR] Cleaves the GlcNAc-Asn bond which joins oligosaccharides to the peptide of asparagine-linked glycoproteins. Requires that the glycosylated asparagine moiety is not substituted on its N-(R1) and C- (R2) terminus.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Asparaginase 3D structures|Asparaginase 3D structures]]
*[[Glycosylasparaginase|Glycosylasparaginase]]
*[[Glycosylasparaginase|Glycosylasparaginase]]
== References ==
== References ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Atcc 13253]]
[[Category: Elizabethkingia meningoseptica]]
[[Category: Guo, H C]]
[[Category: Large Structures]]
[[Category: Xu, Q]]
[[Category: Guo H-C]]
[[Category: Autoproteolysis]]
[[Category: Xu Q]]
[[Category: Glycosylasparaginase]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Mutant]]
[[Category: N-terminal nucleophile]]
[[Category: Precursor]]

Latest revision as of 18:20, 20 September 2023

PRECURSOR OF THE W11F MUTANT GLYCOSYLASPARAGINASE FROM FLAVOBACTERIUM MENINGOSEPTICUM

9gaf, resolution 1.90Å

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