Pho4: Difference between revisions
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<StructureSection load='' size='400' side='right' caption='Yeast Pho4 DNA-binding domain complex with DNA (PDB code [[1a0a]]) ' scene='72/725407/Cv/1' pspeed='8'> | –<StructureSection load='' size='400' side='right' caption='Yeast Pho4 DNA-binding domain complex with DNA (PDB code [[1a0a]]) ' scene='72/725407/Cv/1' pspeed='8'> | ||
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*DNA binding | *DNA binding | ||
The Pho4 protein binds to DNA as a homodimer, and the binding region binds specifically to E-box sequence CACGTG and it's 3'-flanking bases by a specific subset of the basic region of the bHLH motif.<ref>PMID:1861859</ref> | |||
the residues who takes part in the E-box recognition are His5, Glu9, and Arg13.<ref>PMID:1170095</ref> | the residues who takes part in the E-box recognition are His5, Glu9, and Arg13.<ref>PMID:1170095</ref> | ||
