5xet: Difference between revisions
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==Crystal structure of Mycobacterium tuberculosis methionyl-tRNA synthetase bound by methionyl-adenylate (Met-AMP)== | |||
<StructureSection load='5xet' size='340' side='right' caption='[[5xet]], [[Resolution|resolution]] 2.38Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5xet]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XET OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XET FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ME8:[[(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHOXY-HYDROXY-PHOSPHORYL]+(2S)-2-AZANYL-4-METHYLSULFANYL-BUTANOATE'>ME8</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine--tRNA_ligase Methionine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.10 6.1.1.10] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xet FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xet OCA], [http://pdbe.org/5xet PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xet RCSB], [http://www.ebi.ac.uk/pdbsum/5xet PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xet ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/A5U150_MYCTA A5U150_MYCTA]] Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.[HAMAP-Rule:MF_01228] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Methionine--tRNA ligase]] | |||
[[Category: Cui, S]] | |||
[[Category: Gao, X]] | |||
[[Category: Qin, B]] | |||
[[Category: Wang, M]] | |||
[[Category: Wang, W]] | |||
[[Category: Wojdyla, J A]] | |||
[[Category: Aminoacyl-trna synthetase]] | |||
[[Category: Atp]] | |||
[[Category: Complex]] | |||
[[Category: Ligase]] | |||
[[Category: Synthetase]] | |||
Revision as of 05:37, 11 July 2018
Crystal structure of Mycobacterium tuberculosis methionyl-tRNA synthetase bound by methionyl-adenylate (Met-AMP)
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