6fz6: Difference between revisions
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==Crystal Structure of a radical SAM methyltransferase from Sphaerobacter thermophilus== | |||
<StructureSection load='6fz6' size='340' side='right'caption='[[6fz6]], [[Resolution|resolution]] 1.42Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6fz6]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FZ6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FZ6 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr> | |||
[[Category: | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SMC:S-METHYLCYSTEINE'>SMC</scene></td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/23S_rRNA_(adenine(2503)-C(2))-methyltransferase 23S rRNA (adenine(2503)-C(2))-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.192 2.1.1.192] </span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fz6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fz6 OCA], [http://pdbe.org/6fz6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fz6 RCSB], [http://www.ebi.ac.uk/pdbsum/6fz6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fz6 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/D1C4T7_SPHTD D1C4T7_SPHTD]] Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.[HAMAP-Rule:MF_01849][SAAS:SAAS00721833] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Hinchliffe, P]] | |||
[[Category: Shaw, J M]] | |||
[[Category: Spencer, J]] | |||
[[Category: Antibiotic resistance]] | |||
[[Category: Methyltransferase]] | |||
[[Category: Radical sam]] | |||
[[Category: Rrna]] | |||
[[Category: Transferase]] | |||
Revision as of 07:14, 10 April 2019
Crystal Structure of a radical SAM methyltransferase from Sphaerobacter thermophilus
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