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| | | #REDIRECT [[5yzi]] This PDB entry is obsolete and replaced by 5yzi |
| ==Crystal Structure of Mouse Cytosolic Isocitrate Dehydrogenase complexed with Cadmium and citrate==
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| <StructureSection load='2cmv' size='340' side='right' caption='[[2cmv]], [[Resolution|resolution]] 2.52Å' scene=''>
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| == Structural highlights ==
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| <table><tr><td colspan='2'>[[2cmv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CMV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CMV FirstGlance]. <br>
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| </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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| <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2cmj|2cmj]]</td></tr>
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| <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Isocitrate_dehydrogenase_(NADP(+)) Isocitrate dehydrogenase (NADP(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.42 1.1.1.42] </span></td></tr>
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| <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cmv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cmv OCA], [http://pdbe.org/2cmv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cmv RCSB], [http://www.ebi.ac.uk/pdbsum/2cmv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2cmv ProSAT]</span></td></tr>
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| </table>
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| == Evolutionary Conservation ==
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| [[Image:Consurf_key_small.gif|200px|right]]
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| Check<jmol>
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| <jmolCheckbox>
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| <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cm/2cmv_consurf.spt"</scriptWhenChecked>
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| <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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| <text>to colour the structure by Evolutionary Conservation</text>
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| </jmolCheckbox>
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| </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cmv ConSurf].
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| <div style="clear:both"></div>
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| ==See Also==
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| *[[Isocitrate dehydrogenase|Isocitrate dehydrogenase]]
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| *[[Recombinase A|Recombinase A]]
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| __TOC__
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| </StructureSection>
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| [[Category: Lk3 transgenic mice]]
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| [[Category: Cho, H J]]
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| [[Category: Huh, T L]]
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| [[Category: Kang, B S]]
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| [[Category: Kim, K J]]
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| [[Category: Cadmium]]
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| [[Category: Glyoxylate bypass]]
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| [[Category: Isocitrate dehydrogenase]]
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| [[Category: Nadp]]
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| [[Category: Oxidoreductase]]
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| [[Category: Tricarboxylic acid cycle]]
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