2gmv: Difference between revisions

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3,330,058 edits
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[[Image:2gmv.gif|left|200px]]
[[Image:2gmv.gif|left|200px]]


{{Structure
<!--
|PDB= 2gmv |SIZE=350|CAPTION= <scene name='initialview01'>2gmv</scene>, resolution 2.30&Aring;
The line below this paragraph, containing "STRUCTURE_2gmv", creates the "Structure Box" on the page.
|SITE=
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
|LIGAND= <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PEP:PHOSPHOENOLPYRUVATE'>PEP</scene>, <scene name='pdbligand=UN8:N-(4-{[3-BUTYL-1-(2-FLUOROBENZYL)-2,6-DIOXO-2,3,6,7-TETRAHYDRO-1H-PURIN-8-YL]METHYL}PHENYL)-1-METHYL-1H-IMIDAZOLE-4-SULFONAMIDE'>UN8</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoenolpyruvate_carboxykinase_(GTP) Phosphoenolpyruvate carboxykinase (GTP)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.32 4.1.1.32] </span>
or leave the SCENE parameter empty for the default display.
|GENE= PCK1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
-->
|DOMAIN=
{{STRUCTURE_2gmv| PDB=2gmv  | SCENE= }}  
|RELATEDENTRY=[[1khb|1KHB]], [[1nhx|1NHX]], [[1m51|1M51]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gmv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gmv OCA], [http://www.ebi.ac.uk/pdbsum/2gmv PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2gmv RCSB]</span>
}}


'''PEPCK complex with a GTP-competitive inhibitor'''
'''PEPCK complex with a GTP-competitive inhibitor'''
Line 27: Line 24:
C-8 Modifications of 3-alkyl-1,8-dibenzylxanthines as inhibitors of human cytosolic phosphoenolpyruvate carboxykinase., Pietranico SL, Foley LH, Huby N, Yun W, Dunten P, Vermeulen J, Wang P, Toth K, Ramsey G, Gubler ML, Wertheimer SJ, Bioorg Med Chem Lett. 2007 Jul 15;17(14):3835-9. Epub 2007 May 22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17532214 17532214]
C-8 Modifications of 3-alkyl-1,8-dibenzylxanthines as inhibitors of human cytosolic phosphoenolpyruvate carboxykinase., Pietranico SL, Foley LH, Huby N, Yun W, Dunten P, Vermeulen J, Wang P, Toth K, Ramsey G, Gubler ML, Wertheimer SJ, Bioorg Med Chem Lett. 2007 Jul 15;17(14):3835-9. Epub 2007 May 22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17532214 17532214]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Phosphoenolpyruvate carboxykinase (GTP)]]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Dunten, P.]]
[[Category: Dunten, P.]]
[[Category: gluconeogenesis]]
[[Category: Gluconeogenesis]]
[[Category: inhibitor]]
[[Category: Inhibitor]]
[[Category: xanthine]]
[[Category: Xanthine]]
 
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