5y3i: Difference between revisions

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~~'''Unreleased structure'''~~

~~The entry~~ 5y3i is ~~ON HOLD~~ ~~until Paper Publication~~

==Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-N-hydroxy-4-methyl-2-(3-(3-methylbenzyl)ureido)pentanamide==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[5y3i]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Y3I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5Y3I FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8N3:(2R)-4-methyl-2-[(3-methylphenyl)methylcarbamoylamino]-N-oxidanyl-pentanamide'>8N3</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5y3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5y3i OCA], [http://pdbe.org/5y3i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5y3i RCSB], [http://www.ebi.ac.uk/pdbsum/5y3i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5y3i ProSAT]</span></td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/AMP1_PLAFQ AMP1_PLAFQ]] Displays aminopeptidase activity with a broad substrate specificity. Preferentially hydrolyzes L-Lys-AMC but also shows strong activity against L-Ala-AMC, L-Arg-AMC and L-Leu-AMC.<ref>PMID:12166515</ref> <ref>PMID:19196988</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Addlagatta, A]]

[[Category: Marapaka, A K]]

[[Category: Zhang, Y]]

[[Category: Aminopeptidase]]

[[Category: Hydrolase]]

[[Category: M1-family]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5y3i is ON HOLD  until Paper Publication
+==Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-N-hydroxy-4-methyl-2-(3-(3-methylbenzyl)ureido)pentanamide==
+<StructureSection load='5y3i' size='340' side='right' caption='[[5y3i]], [[Resolution|resolution]] 1.73&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5y3i]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Y3I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5Y3I FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8N3:(2R)-4-methyl-2-[(3-methylphenyl)methylcarbamoylamino]-N-oxidanyl-pentanamide'>8N3</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5y3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5y3i OCA], [http://pdbe.org/5y3i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5y3i RCSB], [http://www.ebi.ac.uk/pdbsum/5y3i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5y3i ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/AMP1_PLAFQ AMP1_PLAFQ]] Displays aminopeptidase activity with a broad substrate specificity. Preferentially hydrolyzes L-Lys-AMC but also shows strong activity against L-Ala-AMC, L-Arg-AMC and L-Leu-AMC.<ref>PMID:12166515</ref> <ref>PMID:19196988</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Addlagatta, A]]
+[[Category: Marapaka, A K]]
+[[Category: Zhang, Y]]
+[[Category: Aminopeptidase]]
+[[Category: Hydrolase]]
+[[Category: M1-family]]