6d1x: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry 6d1x is ON HOLD~~

==N-Domain Of Grp94, with the Charged Domain, In Complex With the Novel Ligand N-Propyl Carboxyamido Adenosine==

~~Authors: Gewirth, D.T., Immormino, R.M.~~

== Structural highlights ==

<table><tr><td colspan='2'>[[6d1x]] is a 1 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1u0y 1u0y]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6D1X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6D1X FirstGlance]. <br>

~~Description:~~ N-Domain Of Grp94, with the Charged Domain, In Complex With the Novel Ligand N-Propyl Carboxyamido Adenosine

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PA7:N-PROPYL+CARBOXYAMIDO+ADENOSINE'>PA7</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6d1x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6d1x OCA], [http://pdbe.org/6d1x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6d1x RCSB], [http://www.ebi.ac.uk/pdbsum/6d1x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6d1x ProSAT]</span></td></tr>

[[Category: Immormino, R.M]]

</table>

[[Category: ~~Gewirth, D.T~~]]

== Function ==

[[http://www.uniprot.org/uniprot/ENPL_CANLF ENPL_CANLF]] Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity (By similarity).

__TOC__

</StructureSection>

[[Category: Gewirth, D T]]

[[Category: Immormino, R M]]

[[Category: Chaperone]]

[[Category: Co-crystal]]

[[Category: Hsp90]]

[[Category: Inhibitor]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6d1x is ON HOLD
+==N-Domain Of Grp94, with the Charged Domain, In Complex With the Novel Ligand N-Propyl Carboxyamido Adenosine==
+<StructureSection load='6d1x' size='340' side='right' caption='[[6d1x]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-Authors: Gewirth, D.T., Immormino, R.M.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6d1x]] is a 1 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1u0y 1u0y]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6D1X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6D1X FirstGlance]. <br>
-Description: N-Domain Of Grp94, with the Charged Domain, In Complex With the Novel Ligand N-Propyl Carboxyamido Adenosine
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PA7:N-PROPYL+CARBOXYAMIDO+ADENOSINE'>PA7</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6d1x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6d1x OCA], [http://pdbe.org/6d1x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6d1x RCSB], [http://www.ebi.ac.uk/pdbsum/6d1x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6d1x ProSAT]</span></td></tr>
-[[Category: Immormino, R.M]]
+</table>
-[[Category: Gewirth, D.T]]
+== Function ==
+[[http://www.uniprot.org/uniprot/ENPL_CANLF ENPL_CANLF]] Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity (By similarity).
+__TOC__
+</StructureSection>
+[[Category: Gewirth, D T]]
+[[Category: Immormino, R M]]
+[[Category: Chaperone]]
+[[Category: Co-crystal]]
+[[Category: Hsp90]]
+[[Category: Inhibitor]]