6g2d: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6g2d is ~~ON HOLD~~ ~~until Paper Publication~~

==Citrate-induced acetyl-CoA carboxylase (ACC-Cit) filament at 5.4 A resolution==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[6g2d]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6G2D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6G2D FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6g2d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6g2d OCA], [http://pdbe.org/6g2d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6g2d RCSB], [http://www.ebi.ac.uk/pdbsum/6g2d PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6g2d ProSAT]</span></td></tr>

[[Category: ~~Unreleased Structures~~]]

</table>

== Disease ==

[[http://www.uniprot.org/uniprot/ACACA_HUMAN ACACA_HUMAN]] Defects in ACACA are a cause of acetyl-CoA carboxylase 1 deficiency (ACACAD) [MIM:[http://omim.org/entry/613933 613933]]; also known as ACAC deficiency or ACC deficiency. An inborn error of de novo fatty acid synthesis associated with severe brain damage, persistent myopathy and poor growth.<ref>PMID:6114432</ref>

== Function ==

[[http://www.uniprot.org/uniprot/ACACA_HUMAN ACACA_HUMAN]] Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.<ref>PMID:20952656</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Chami, M]]

[[Category: Hagmann, A]]

[[Category: Hunkeler, M]]

[[Category: Maier, T]]

[[Category: Stahlberg, H]]

[[Category: Stuttfeld, E]]

[[Category: Biotin-dependent carboxylase]]

[[Category: Filament]]

[[Category: Helical]]

[[Category: Ligase]]

[[Category: Multienzyme]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6g2d is ON HOLD  until Paper Publication
+==Citrate-induced acetyl-CoA carboxylase (ACC-Cit) filament at 5.4 A resolution==
+<StructureSection load='6g2d' size='340' side='right' caption='[[6g2d]], [[Resolution|resolution]] 5.40&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6g2d]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6G2D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6G2D FirstGlance]. <br>
-Description:
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6g2d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6g2d OCA], [http://pdbe.org/6g2d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6g2d RCSB], [http://www.ebi.ac.uk/pdbsum/6g2d PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6g2d ProSAT]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
+== Disease ==
+[[http://www.uniprot.org/uniprot/ACACA_HUMAN ACACA_HUMAN]] Defects in ACACA are a cause of acetyl-CoA carboxylase 1 deficiency (ACACAD) [MIM:[http://omim.org/entry/613933 613933]]; also known as ACAC deficiency or ACC deficiency. An inborn error of de novo fatty acid synthesis associated with severe brain damage, persistent myopathy and poor growth.<ref>PMID:6114432</ref>
+== Function ==
+[[http://www.uniprot.org/uniprot/ACACA_HUMAN ACACA_HUMAN]] Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.<ref>PMID:20952656</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Chami, M]]
+[[Category: Hagmann, A]]
+[[Category: Hunkeler, M]]
+[[Category: Maier, T]]
+[[Category: Stahlberg, H]]
+[[Category: Stuttfeld, E]]
+[[Category: Biotin-dependent carboxylase]]
+[[Category: Filament]]
+[[Category: Helical]]
+[[Category: Ligase]]
+[[Category: Multienzyme]]