6gap: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6gap is ~~ON HOLD~~

==Crystal structure of the T3D reovirus sigma1 coiled coil tail and body==

~~Authors~~: ~~Dietrich~~, M.H., ~~Stehle~~, T.

== Structural highlights ==

<table><tr><td colspan='2'>[[6gap]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GAP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GAP FirstGlance]. <br>

~~Description: Crystal structure of the T3D reovirus sigma1 coiled coil tail and body~~

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gap FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gap OCA], [http://pdbe.org/6gap PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gap RCSB], [http://www.ebi.ac.uk/pdbsum/6gap PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gap ProSAT]</span></td></tr>

[[~~Category~~: ~~Unreleased Structures~~]]

</table>

[[Category: Dietrich, M.H]]

== Function ==

[[http://www.uniprot.org/uniprot/SIGM1_REOVD SIGM1_REOVD]] Fiber-like molecule that attaches the virion to the host cell membrane by binding to the primary receptor F11R/JAM-A and to sialic acid containing proteins (coreceptor). The interaction of sigma-1 with F11R is required for NF-kB activation and apoptosis. Binding to both sialic acid and F11R is required to induce maximal levels of apoptosis.

__TOC__

</StructureSection>

[[Category: Dietrich, M H]]

[[Category: Stehle, T]]

[[Category: Beta-spiral repeat]]

[[Category: Cell attachment protein]]

[[Category: Coiled coil]]

[[Category: Reovirus sigma1]]

[[Category: Viral protein]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6gap is ON HOLD
+==Crystal structure of the T3D reovirus sigma1 coiled coil tail and body==
+<StructureSection load='6gap' size='340' side='right' caption='[[6gap]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
-Authors: Dietrich, M.H., Stehle, T.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6gap]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GAP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GAP FirstGlance]. <br>
-Description: Crystal structure of the T3D reovirus sigma1 coiled coil tail and body
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gap FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gap OCA], [http://pdbe.org/6gap PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gap RCSB], [http://www.ebi.ac.uk/pdbsum/6gap PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gap ProSAT]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
-[[Category: Dietrich, M.H]]
+== Function ==
+[[http://www.uniprot.org/uniprot/SIGM1_REOVD SIGM1_REOVD]] Fiber-like molecule that attaches the virion to the host cell membrane by binding to the primary receptor F11R/JAM-A and to sialic acid containing proteins (coreceptor). The interaction of sigma-1 with F11R is required for NF-kB activation and apoptosis. Binding to both sialic acid and F11R is required to induce maximal levels of apoptosis.
+__TOC__
+</StructureSection>
+[[Category: Dietrich, M H]]
 [[Category: Stehle, T]]
+[[Category: Beta-spiral repeat]]
+[[Category: Cell attachment protein]]
+[[Category: Coiled coil]]
+[[Category: Reovirus sigma1]]
+[[Category: Viral protein]]