5f87: Difference between revisions

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==Crystal structure of Drosophila Poglut1 (Rumi) complexed with UDP==
==Crystal structure of Drosophila Poglut1 (Rumi) complexed with UDP==
<StructureSection load='5f87' size='340' side='right' caption='[[5f87]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
<StructureSection load='5f87' size='340' side='right'caption='[[5f87]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5f87]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F87 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5F87 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5f87]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F87 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5F87 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5f85|5f85]], [[5f86|5f86]], [[5f84|5f84]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rumi, CG31152 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5f87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5f87 OCA], [https://pdbe.org/5f87 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5f87 RCSB], [https://www.ebi.ac.uk/pdbsum/5f87 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5f87 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5f87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5f87 OCA], [http://pdbe.org/5f87 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5f87 RCSB], [http://www.ebi.ac.uk/pdbsum/5f87 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5f87 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/RUMI_DROME RUMI_DROME]] Protein O-glucosyltransferase. Catalyzes the reaction that attaches glucose through an O-glycosidic linkage to a conserved serine residue in epidermal growth factor-like repeats. Regulates Notch signaling by glucosylating Notch in the ER, glucosylation is required for the correct folding and cleavage of Notch.<ref>PMID:18243100</ref>
[https://www.uniprot.org/uniprot/RUMI_DROME RUMI_DROME] Protein O-glucosyltransferase. Catalyzes the reaction that attaches glucose through an O-glycosidic linkage to a conserved serine residue in epidermal growth factor-like repeats. Regulates Notch signaling by glucosylating Notch in the ER, glucosylation is required for the correct folding and cleavage of Notch.<ref>PMID:18243100</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Drome]]
[[Category: Drosophila melanogaster]]
[[Category: Li, H L]]
[[Category: Large Structures]]
[[Category: Yu, H J]]
[[Category: Li HL]]
[[Category: Egf repeat]]
[[Category: Yu HJ]]
[[Category: Glycosyltransferase]]
[[Category: Notch regulation]]
[[Category: Protein o-glucosyltransferase]]
[[Category: Transferase]]