Sandbox GGC13: Difference between revisions

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== Structural highlights ==

Lactate dehydrogenase is a tetramer protein which can form five different isoenzymes. Lactate dehydrogenase subunits exist primarily in two isoforms: M and H, which differ in a single residue. The M subunit contains an alanine while the H subunit contains a glutamine. The combination of subunits defines which isoenzyme is formed and indicates where the enzyme will be present in the body. Lactate dehydrogenase A is composed of four M subunits.

Lactate dehydrogenase is a tetramer protein which can form five different isoenzymes. Lactate dehydrogenase subunits exist primarily in two isoforms: M and H, which differ in a single residue. The M subunit contains an alanine while the H subunit contains a glutamine. The combination of subunits defines which isoenzyme is formed and indicates where the enzyme will be present in the body. Lactate dehydrogenase A is composed of four M subunits. The subunits can adopt two conformations, open and closed, which determine the subunits activity.

<scene name='78/781197/Oxamate/1'>Interactions between the A-chain subunit and the inhibitor, oxamate. The substrate active site to which oxamate is bound is in the closed conformation.</scene>

This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.

Sandbox GGC13: Difference between revisions

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 == Structural highlights ==
-Lactate dehydrogenase is a tetramer protein which can form five different isoenzymes.  Lactate dehydrogenase subunits exist primarily in two isoforms: M and H, which differ in a single residue.  The M subunit contains an alanine while the H subunit contains a glutamine.  The combination of subunits defines which isoenzyme is formed and indicates where the enzyme will be present in the body.  Lactate dehydrogenase A is composed of four M subunits.
+Lactate dehydrogenase is a tetramer protein which can form five different isoenzymes.  Lactate dehydrogenase subunits exist primarily in two isoforms: M and H, which differ in a single residue.  The M subunit contains an alanine while the H subunit contains a glutamine.  The combination of subunits defines which isoenzyme is formed and indicates where the enzyme will be present in the body.  Lactate dehydrogenase A is composed of four M subunits.  The subunits can adopt two conformations, open and closed, which determine the subunits activity.
+<scene name='78/781197/Oxamate/1'>Interactions between the A-chain subunit and the inhibitor, oxamate.  The substrate active site to which oxamate is bound is in the closed conformation.</scene>
 This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.