5zng: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

The ~~entry~~ 5zng is ~~ON HOLD until Paper Publication~~

==The crystal complex of immune receptor RGA5A_S of Pia from rice (Oryzae sativa) with rice blast (Magnaporthe oryzae) effector protein AVR1-CO39==

~~Authors~~: ~~Guo, L~~.W., ~~Zhang, Y~~.K., ~~Liu~~, Q.~~, Ma, M~~.Q., ~~Liu, J~~.F., ~~Peng, Y~~.L.

== Structural highlights ==

<table><tr><td colspan='2'>[[5zng]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZNG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZNG FirstGlance]. <br>

~~Description~~: ~~The crystal complex of immune receptor RGA5A_S~~ of Pia from ~~rice~~ (~~Oryzae sativa~~) ~~with rice blast~~ (~~Magnaporthe oryzae~~) ~~effector protein~~ AVR1-CO39

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zng OCA], [http://pdbe.org/5zng PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zng RCSB], [http://www.ebi.ac.uk/pdbsum/5zng PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zng ProSAT]</span></td></tr>

~~[[Category: Unreleased Structures]]~~

</table>

[[Category: ~~Peng~~, Y.L]]

== Function ==

[[Category: ~~Guo~~, ~~L.W~~]]

[[http://www.uniprot.org/uniprot/RGA5R_ORYSJ RGA5R_ORYSJ]] Disease resistance (R) protein that recognizes the AVR-Pia and AVR1-CO39 effector avirulence proteins from M.oryzae. Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth. Contribution of RGA4 is required to recognize the effector avirulence proteins AVR-Pia and AVR1-CO39 from M.oryzae (PubMed:21251109, PubMed:23548743). Acts as a repressor of the RGA4-mediated cell death activation. Upon infection, recognition and binding of the AVR effectors relieve the RGA5-mediated repression and triggers the hypersensitive response (PubMed:25024433). Immune response triggered by the RGA4-RGA5 -mediated recognition of AVR1-CO39 confers resistance to X.oryzae pathovars (PubMed:27289079).<ref>PMID:21251109</ref> <ref>PMID:23548743</ref> <ref>PMID:25024433</ref> <ref>PMID:27289079</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Guo, L W]]

[[Category: Liu, J F]]

[[Category: Liu, Q]]

[[Category: ~~Liu~~, ~~J.F~~]]

[[Category: Ma, M Q]]

[[Category: Zhang, Y.K]]

[[Category: Peng, Y L]]

[[Category: ~~Ma, M.Q~~]]

[[Category: Zhang, Y K]]

[[Category: Effector protein]]

[[Category: Immune system]]

[[Category: Magnaporthe oryzae]]

[[Category: Resistance protein]]

[[Category: Rga5a_]]

[[Category: Rice avr1-co39]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5zng is ON HOLD  until Paper Publication
+==The crystal complex of immune receptor RGA5A_S of Pia from rice (Oryzae sativa) with rice blast (Magnaporthe oryzae) effector protein AVR1-CO39==
+<StructureSection load='5zng' size='340' side='right' caption='[[5zng]], [[Resolution|resolution]] 2.19&Aring;' scene=''>
-Authors: Guo, L.W., Zhang, Y.K., Liu, Q., Ma, M.Q., Liu, J.F., Peng, Y.L.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5zng]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZNG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZNG FirstGlance]. <br>
-Description: The crystal complex of immune receptor RGA5A_S of Pia from rice (Oryzae sativa) with rice blast (Magnaporthe oryzae) effector protein AVR1-CO39
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zng OCA], [http://pdbe.org/5zng PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zng RCSB], [http://www.ebi.ac.uk/pdbsum/5zng PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zng ProSAT]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
-[[Category: Peng, Y.L]]
+== Function ==
-[[Category: Guo, L.W]]
+[[http://www.uniprot.org/uniprot/RGA5R_ORYSJ RGA5R_ORYSJ]] Disease resistance (R) protein that recognizes the AVR-Pia and AVR1-CO39 effector avirulence proteins from M.oryzae. Resistance proteins guard the plant against pathogens that contain an appropriate avirulence protein via an indirect interaction with this avirulence protein. That triggers a defense system including the hypersensitive response, which restricts the pathogen growth. Contribution of RGA4 is required to recognize the effector avirulence proteins AVR-Pia and AVR1-CO39 from M.oryzae (PubMed:21251109, PubMed:23548743). Acts as a repressor of the RGA4-mediated cell death activation. Upon infection, recognition and binding of the AVR effectors relieve the RGA5-mediated repression and triggers the hypersensitive response (PubMed:25024433). Immune response triggered by the RGA4-RGA5 -mediated recognition of AVR1-CO39 confers resistance to X.oryzae pathovars (PubMed:27289079).<ref>PMID:21251109</ref> <ref>PMID:23548743</ref> <ref>PMID:25024433</ref> <ref>PMID:27289079</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Guo, L W]]
+[[Category: Liu, J F]]
 [[Category: Liu, Q]]
-[[Category: Liu, J.F]]
+[[Category: Ma, M Q]]
-[[Category: Zhang, Y.K]]
+[[Category: Peng, Y L]]
-[[Category: Ma, M.Q]]
+[[Category: Zhang, Y K]]
+[[Category: Effector protein]]
+[[Category: Immune system]]
+[[Category: Magnaporthe oryzae]]
+[[Category: Resistance protein]]
+[[Category: Rga5a_]]
+[[Category: Rice avr1-co39]]