6cyi: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6cyi is ~~ON HOLD until Paper Publication~~

==Grp94 N-domain bound to NEOCA==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[6cyi]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CYI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CYI FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=N5O:5-N-(2-HYDROXYL)ETHYL+CARBOXYAMIDO+ADENOSINE'>N5O</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cyi OCA], [http://pdbe.org/6cyi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cyi RCSB], [http://www.ebi.ac.uk/pdbsum/6cyi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cyi ProSAT]</span></td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/ENPL_CANLF ENPL_CANLF]] Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity (By similarity).

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Aw, W J]]

[[Category: Gewirth, D T]]

[[Category: Huck, J D]]

[[Category: Chaperone]]

[[Category: Chaperone-inhibitor complex]]

[[Category: Endoplasmic reticulum]]

[[Category: Grp94]]

[[Category: Hsp90]]

[[Category: Inhibitor]]

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-'''Unreleased structure'''
-The entry 6cyi is ON HOLD  until Paper Publication
+==Grp94 N-domain bound to NEOCA==
+<StructureSection load='6cyi' size='340' side='right'caption='[[6cyi]], [[Resolution|resolution]] 1.76&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6cyi]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CYI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CYI FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=N5O:5-N-(2-HYDROXYL)ETHYL+CARBOXYAMIDO+ADENOSINE'>N5O</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cyi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cyi OCA], [http://pdbe.org/6cyi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cyi RCSB], [http://www.ebi.ac.uk/pdbsum/6cyi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cyi ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/ENPL_CANLF ENPL_CANLF]] Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity (By similarity).
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Aw, W J]]
+[[Category: Gewirth, D T]]
+[[Category: Huck, J D]]
+[[Category: Chaperone]]
+[[Category: Chaperone-inhibitor complex]]
+[[Category: Endoplasmic reticulum]]
+[[Category: Grp94]]
+[[Category: Hsp90]]
+[[Category: Inhibitor]]