1ztr: Difference between revisions
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==Solution structure of Engrailed homeodomain L16A mutant== | ==Solution structure of Engrailed homeodomain L16A mutant== | ||
<StructureSection load='1ztr' size='340' side='right' caption='[[1ztr]], [[NMR_Ensembles_of_Models | 25 NMR models]]' scene=''> | <StructureSection load='1ztr' size='340' side='right'caption='[[1ztr]], [[NMR_Ensembles_of_Models | 25 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1ztr]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[1ztr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drome Drome]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZTR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZTR FirstGlance]. <br> | ||
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1enh|1enh]]</td></tr> | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1enh|1enh]]</div></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">en ([ | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">en ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ztr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ztr OCA], [https://pdbe.org/1ztr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ztr RCSB], [https://www.ebi.ac.uk/pdbsum/1ztr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ztr ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/HMEN_DROME HMEN_DROME]] This protein specifies the body segmentation pattern. It is required for the development of the central nervous system. Transcriptional regulator that represses activated promoters. Wg signaling operates by inactivating the SGG repression of EN autoactivation. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Drome]] | [[Category: Drome]] | ||
[[Category: Large Structures]] | |||
[[Category: Fersht, A R]] | [[Category: Fersht, A R]] | ||
[[Category: Freund, S M.V]] | [[Category: Freund, S M.V]] | ||