6dbp: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6dbp is ~~ON HOLD until Paper Publication~~

==RNA-recognition motif 1 of human MSI2==

~~Authors~~: ~~Goldgur~~, Y., ~~Kharas~~, M.G., ~~Minuesa~~, G.

== Structural highlights ==

<table><tr><td colspan='2'>[[6dbp]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DBP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DBP FirstGlance]. <br>

~~Description~~: RNA~~-recognition motif 1~~ of ~~human MSI2~~

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dbp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dbp OCA], [http://pdbe.org/6dbp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dbp RCSB], [http://www.ebi.ac.uk/pdbsum/6dbp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dbp ProSAT]</span></td></tr>

[[Category: ~~Unreleased~~ Structures]]

</table>

== Disease ==

[[http://www.uniprot.org/uniprot/MSI2H_HUMAN MSI2H_HUMAN]] Chromosomal aberrations involving MSI2 may contribute to disease progression in chronic myeloid leukemia. Translocation t(7;17)(p15;q23) with HOXA9; translocation t(7;17)(q32-34;q23).<ref>PMID:12649177</ref>

== Function ==

[[http://www.uniprot.org/uniprot/MSI2H_HUMAN MSI2H_HUMAN]] RNA binding protein that regulates the expression of target mRNAs at the translation level. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity).

== References ==

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Goldgur, Y]]

[[Category: Kharas, M G]]

[[Category: Minuesa, G]]

[[Category: ~~Goldgur, Y~~]]

[[Category: Musashi2 rna recognition motif]]

[[Category: ~~Kharas, M.G~~]]

[[Category: Rna binding protein]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6dbp is ON HOLD  until Paper Publication
+==RNA-recognition motif 1 of human MSI2==
+<StructureSection load='6dbp' size='340' side='right'caption='[[6dbp]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
-Authors: Goldgur, Y., Kharas, M.G., Minuesa, G.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6dbp]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DBP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DBP FirstGlance]. <br>
-Description: RNA-recognition motif 1 of human MSI2
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dbp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dbp OCA], [http://pdbe.org/6dbp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dbp RCSB], [http://www.ebi.ac.uk/pdbsum/6dbp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dbp ProSAT]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
+== Disease ==
+[[http://www.uniprot.org/uniprot/MSI2H_HUMAN MSI2H_HUMAN]] Chromosomal aberrations involving MSI2 may contribute to disease progression in chronic myeloid leukemia. Translocation t(7;17)(p15;q23) with HOXA9; translocation t(7;17)(q32-34;q23).<ref>PMID:12649177</ref>
+== Function ==
+[[http://www.uniprot.org/uniprot/MSI2H_HUMAN MSI2H_HUMAN]] RNA binding protein that regulates the expression of target mRNAs at the translation level. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity).
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Goldgur, Y]]
+[[Category: Kharas, M G]]
 [[Category: Minuesa, G]]
-[[Category: Goldgur, Y]]
+[[Category: Musashi2 rna recognition motif]]
-[[Category: Kharas, M.G]]
+[[Category: Rna binding protein]]