6d15: Difference between revisions

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'''Unreleased structure'''


The entry 6d15 is ON HOLD  until Paper Publication
==Crystal structure of KPC-2 complexed with compound 1==
 
<StructureSection load='6d15' size='340' side='right'caption='[[6d15]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6d15]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6D15 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6D15 FirstGlance]. <br>
Description:  
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=TWB:[(6,7-dimethyl-2-oxo-2H-1-benzopyran-4-yl)methyl]phosphonic+acid'>TWB</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6d15 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6d15 OCA], [http://pdbe.org/6d15 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6d15 RCSB], [http://www.ebi.ac.uk/pdbsum/6d15 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6d15 ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/BLKPC_KLEPN BLKPC_KLEPN]] Hydrolyzes carbapenems, penicillins, cephalosporins and monobactams with varying efficiency.
__TOC__
</StructureSection>
[[Category: Beta-lactamase]]
[[Category: Large Structures]]
[[Category: Chen, Y]]
[[Category: Pemberton, O A]]
[[Category: Carbapenemase]]
[[Category: Hydrolase]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Inhibitor]]
[[Category: Phosphonate]]

Revision as of 05:51, 17 April 2019

Crystal structure of KPC-2 complexed with compound 1

6d15, resolution 1.30Å

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