2cp7: Difference between revisions

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==Solution structure of the 1st CAP-Gly domain in mouse CLIP-170/restin==
==Solution structure of the 1st CAP-Gly domain in mouse CLIP-170/restin==
<StructureSection load='2cp7' size='340' side='right' caption='[[2cp7]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2cp7' size='340' side='right'caption='[[2cp7]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2cp7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CP7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CP7 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2cp7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CP7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CP7 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RIKEN cDNA 4631429H07 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RIKEN cDNA 4631429H07 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cp7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cp7 OCA], [http://pdbe.org/2cp7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2cp7 RCSB], [http://www.ebi.ac.uk/pdbsum/2cp7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2cp7 ProSAT], [http://www.topsan.org/Proteins/RSGI/2cp7 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cp7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cp7 OCA], [https://pdbe.org/2cp7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cp7 RCSB], [https://www.ebi.ac.uk/pdbsum/2cp7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cp7 ProSAT], [https://www.topsan.org/Proteins/RSGI/2cp7 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CLIP1_MOUSE CLIP1_MOUSE]] Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth and microtubule bundling. Links cytoplasmic vesicles to microtubules and thereby plays an important role in intracellular vesicle trafficking. Plays a role macropinocytosis and endosome trafficking (By similarity).  
[[https://www.uniprot.org/uniprot/CLIP1_MOUSE CLIP1_MOUSE]] Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth and microtubule bundling. Links cytoplasmic vesicles to microtubules and thereby plays an important role in intracellular vesicle trafficking. Plays a role macropinocytosis and endosome trafficking (By similarity).  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Lk3 transgenic mice]]
[[Category: Inoue, M]]
[[Category: Inoue, M]]