5qhs: Difference between revisions
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==PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FF000014a== | |||
<StructureSection load='5qhs' size='340' side='right' caption='[[5qhs]], [[Resolution|resolution]] 1.95Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5qhs]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QHS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5QHS FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GQV:1-methyl-3-oxidanyl-pyridin-2-one'>GQV</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5qhs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qhs OCA], [http://pdbe.org/5qhs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qhs RCSB], [http://www.ebi.ac.uk/pdbsum/5qhs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qhs ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/FA83B_HUMAN FA83B_HUMAN]] Probable proto-oncogene that functions in the epidermal growth factor receptor/EGFR signaling pathway. May activate both the EGFR itself and downstream RAS/MAPK and PI3K/AKT/TOR signaling cascades.<ref>PMID:22886302</ref> <ref>PMID:23676467</ref> <ref>PMID:23912460</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Arrowsmith, C H]] | |||
[[Category: Bountra, C]] | |||
[[Category: Bufton, J C]] | |||
[[Category: Bullock, A N]] | |||
[[Category: Collins, P]] | [[Category: Collins, P]] | ||
[[Category: | [[Category: Delft, F von]] | ||
[[Category: | [[Category: Douangamath, A]] | ||
[[Category: Edwards, A]] | [[Category: Edwards, A]] | ||
[[Category: | [[Category: Fox, A E]] | ||
[[Category: Krojer, T]] | [[Category: Krojer, T]] | ||
[[Category: | [[Category: Pinkas, D M]] | ||
[[Category: | [[Category: Talon, R]] | ||
[[Category: | [[Category: Zhang, R]] | ||
[[Category: | [[Category: Duf1669 domain]] | ||
[[Category: Pandda]] | |||
[[Category: Protein binding]] | |||
[[Category: Sgc - diamond i04-1 fragment screening]] | |||
[[Category: Xchemexplorer]] | |||
Revision as of 08:05, 19 December 2018
PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of human FAM83B in complex with FF000014a
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