5qic: Difference between revisions
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==PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of HAO1 in complex with Z30620520== | |||
<StructureSection load='5qic' size='340' side='right' caption='[[5qic]], [[Resolution|resolution]] 1.34Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5qic]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QIC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5QIC FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GX4:cyclopropyl-[4-(4-fluorophenyl)piperazin-1-yl]methanone'>GX4</scene></td></tr> | |||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/(S)-2-hydroxy-acid_oxidase (S)-2-hydroxy-acid oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.15 1.1.3.15] </span></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5qic FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qic OCA], [http://pdbe.org/5qic PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qic RCSB], [http://www.ebi.ac.uk/pdbsum/5qic PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qic ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[http://www.uniprot.org/uniprot/HAOX1_HUMAN HAOX1_HUMAN]] Has 2-hydroxyacid oxidase activity. Most active on the 2-carbon substrate glycolate, but is also active on 2-hydroxy fatty acids, with high activity towards 2-hydroxy palmitate and 2-hydroxy octanoate. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Arrowsmith, C H]] | |||
[[Category: Bezerra, G A]] | |||
[[Category: Bountra, C]] | |||
[[Category: Bradley, A R]] | |||
[[Category: Brandao-Neto, J]] | [[Category: Brandao-Neto, J]] | ||
[[Category: Brennan, P E]] | |||
[[Category: Brennan, P | [[Category: Delft, F von]] | ||
[[Category: | [[Category: Douangamath, A]] | ||
[[Category: | |||
[[Category: Edwards, A]] | [[Category: Edwards, A]] | ||
[[Category: Krojer, T]] | [[Category: Krojer, T]] | ||
[[Category: Yue, W | [[Category: MacKinnon, S]] | ||
[[Category: | [[Category: Oppermann, U]] | ||
[[Category: | [[Category: Talon, R]] | ||
[[Category: Yue, W W]] | |||
[[Category: Hao1]] | |||
[[Category: Oxidoreductase]] | |||
[[Category: Pandda]] | |||
[[Category: Sgc - diamond i04-1 fragment screening]] | |||
[[Category: Xchemexplorer]] | |||
Revision as of 07:20, 18 July 2018
PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of HAO1 in complex with Z30620520
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