5zo2: Difference between revisions
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==Crystal structure of mouse nectin-like molecule 4 (mNecl-4) full ectodomain in complex with mouse nectin-like molecule 1 (mNecl-1) Ig1 domain, 3.3A== | |||
<StructureSection load='5zo2' size='340' side='right' caption='[[5zo2]], [[Resolution|resolution]] 3.29Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5zo2]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZO2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZO2 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |||
[[Category: | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1z9m|1z9m]], [[5zo1|5zo1]]</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zo2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zo2 OCA], [http://pdbe.org/5zo2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zo2 RCSB], [http://www.ebi.ac.uk/pdbsum/5zo2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zo2 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/CADM4_MOUSE CADM4_MOUSE]] Involved in the cell-cell adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity. May have tumor-suppressor activity.<ref>PMID:14659875</ref> [[http://www.uniprot.org/uniprot/CADM3_MOUSE CADM3_MOUSE]] Involved in the cell-cell adhesion. Has both calcium-independent homophilic cell-cell adhesion activity and calcium-independent heterophilic cell-cell adhesion activity with IGSF4, NECTIN1 and NECTIN3. Interaction with EPB41L1 may regulate structure or function of cell-cell junctions.<ref>PMID:15741237</ref> <ref>PMID:15893517</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: An, T]] | |||
[[Category: Cui, S]] | |||
[[Category: Fan, Z]] | |||
[[Category: Hu, G]] | |||
[[Category: Ju, W]] | |||
[[Category: Li, C]] | |||
[[Category: Li, D]] | |||
[[Category: Li, J]] | |||
[[Category: Liu, X]] | |||
[[Category: Peng, X]] | |||
[[Category: Qiang, B]] | |||
[[Category: Qin, B]] | |||
[[Category: Shu, P]] | |||
[[Category: Wang, M]] | |||
[[Category: Wojdyla, J A]] | |||
[[Category: Xiang, P]] | |||
[[Category: Yin, B]] | |||
[[Category: Yuan, J]] | |||
[[Category: Axon]] | |||
[[Category: Cadm]] | |||
[[Category: Cell adhesion]] | |||
[[Category: Cell adhesion molecule]] | |||
[[Category: Glycoprotein]] | |||
[[Category: Heterogeneous dimer]] | |||
[[Category: Ig domain]] | |||
[[Category: Molecular replacement]] | |||
[[Category: Myelogenesis]] | |||
[[Category: Necl-1]] | |||
[[Category: Necl-4]] | |||
[[Category: Nectin-like]] | |||
[[Category: Schwann cell]] | |||
[[Category: Syncam]] | |||