6dda: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6dda is ~~ON HOLD until Paper Publication~~

==Nurr1 Covalently Modified by a Dopamine Metabolite==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[6dda]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DDA OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DDA FirstGlance].

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=G7J:5-hydroxy-1,2-dihydro-6H-indol-6-one'>G7J</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='NonStdRes'><td class="sblockLbl">[[Non-Standard_Residue|NonStd Res:]]</td><td class="sblockDat"><scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dda FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dda OCA], [http://pdbe.org/6dda PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dda RCSB], [http://www.ebi.ac.uk/pdbsum/6dda PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dda ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/NR4A2_HUMAN NR4A2_HUMAN]] Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons (By similarity).

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Bhattacharya, P]]

[[Category: Boxue, T]]

[[Category: Bruning, J M]]

[[Category: England, P M]]

[[Category: Fletterick, R J]]

[[Category: Guo, S]]

[[Category: Holton, J M]]

[[Category: Jacobson, M P]]

[[Category: Liu, H]]

[[Category: Otrabella, F]]

[[Category: Wang, Y]]

[[Category: Cysteine adduct]]

[[Category: Dihydroxyindole]]

[[Category: Dopamine]]

[[Category: Nurr1]]

[[Category: Transcription]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6dda is ON HOLD  until Paper Publication
+==Nurr1 Covalently Modified by a Dopamine Metabolite==
+<StructureSection load='6dda' size='340' side='right'caption='[[6dda]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6dda]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DDA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DDA FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=G7J:5-hydroxy-1,2-dihydro-6H-indol-6-one'>G7J</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dda FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dda OCA], [http://pdbe.org/6dda PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dda RCSB], [http://www.ebi.ac.uk/pdbsum/6dda PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dda ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/NR4A2_HUMAN NR4A2_HUMAN]] Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons (By similarity).
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Bhattacharya, P]]
+[[Category: Boxue, T]]
+[[Category: Bruning, J M]]
+[[Category: England, P M]]
+[[Category: Fletterick, R J]]
+[[Category: Guo, S]]
+[[Category: Holton, J M]]
+[[Category: Jacobson, M P]]
+[[Category: Liu, H]]
+[[Category: Otrabella, F]]
+[[Category: Wang, Y]]
+[[Category: Cysteine adduct]]
+[[Category: Dihydroxyindole]]
+[[Category: Dopamine]]
+[[Category: Nurr1]]
+[[Category: Transcription]]