6go4: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6go4 is ~~ON HOLD~~

==TdT chimera (Loop1 of pol mu) - binary complex with ddCTP==

~~Authors~~: ~~Loc~~'h, J., ~~Gerodimos~~, C.A., ~~Rosario~~, S., ~~Lieber~~, M.R., ~~Delarue, M~~.

== Structural highlights ==

<table><tr><td colspan='2'>[[6go4]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GO4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GO4 FirstGlance]. <br>

~~Description~~: ~~TdT chimera~~ (~~Loop1~~ of ~~pol mu)~~ -~~binary complex with ddCTP~~

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DCT:2,3-DIDEOXYCYTIDINE+5-TRIPHOSPHATE'>DCT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6go4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6go4 OCA], [http://pdbe.org/6go4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6go4 RCSB], [http://www.ebi.ac.uk/pdbsum/6go4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6go4 ProSAT]</span></td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/TDT_MOUSE TDT_MOUSE]] Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Delarue, M]]

[[Category: Gerodimos, C A]]

[[Category: Lieber, M R]]

[[Category: Rosario, S]]

[[Category: ~~Loc'~~H, J]]

[[Category: H, J Loc]]

[[Category: ~~Delarue, M~~]]

[[Category: Dna binding protein]]

[[Category: ~~Gerodimos, C.A~~]]

[[Category: Dna bridging]]

[[Category: ~~Lieber, M.R~~]]

[[Category: Dna polymerase polx]]

[[Category: Nhej pathway]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6go4 is ON HOLD
+==TdT chimera (Loop1 of pol mu) - binary complex with ddCTP==
+<StructureSection load='6go4' size='340' side='right'caption='[[6go4]], [[Resolution|resolution]] 1.96&Aring;' scene=''>
-Authors: Loc'h, J., Gerodimos, C.A., Rosario, S., Lieber, M.R., Delarue, M.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6go4]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GO4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GO4 FirstGlance]. <br>
-Description: TdT chimera (Loop1 of pol mu) -binary complex with ddCTP
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DCT:2,3-DIDEOXYCYTIDINE+5-TRIPHOSPHATE'>DCT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6go4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6go4 OCA], [http://pdbe.org/6go4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6go4 RCSB], [http://www.ebi.ac.uk/pdbsum/6go4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6go4 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/TDT_MOUSE TDT_MOUSE]] Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Delarue, M]]
+[[Category: Gerodimos, C A]]
+[[Category: Lieber, M R]]
 [[Category: Rosario, S]]
-[[Category: Loc'H, J]]
+[[Category: H, J Loc]]
-[[Category: Delarue, M]]
+[[Category: Dna binding protein]]
-[[Category: Gerodimos, C.A]]
+[[Category: Dna bridging]]
-[[Category: Lieber, M.R]]
+[[Category: Dna polymerase polx]]
+[[Category: Nhej pathway]]