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==Crystal structure of rRNA methyltransferase with SAM ligand==
==Crystal structure of rRNA methyltransferase with SAM ligand==
<StructureSection load='2egv' size='340' side='right' caption='[[2egv]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
<StructureSection load='2egv' size='340' side='right'caption='[[2egv]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2egv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"aquifex_aeolicus"_huber_and_stetter_2001 "aquifex aeolicus" huber and stetter 2001]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EGV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2EGV FirstGlance]. <br>
<table><tr><td colspan='2'>[[2egv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"aquifex_aeolicus"_huber_and_stetter_2001 "aquifex aeolicus" huber and stetter 2001]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EGV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EGV FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2egw|2egw]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2egw|2egw]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RsmE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=63363 "Aquifex aeolicus" Huber and Stetter 2001])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RsmE ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=63363 "Aquifex aeolicus" Huber and Stetter 2001])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2egv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2egv OCA], [http://pdbe.org/2egv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2egv RCSB], [http://www.ebi.ac.uk/pdbsum/2egv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2egv ProSAT], [http://www.topsan.org/Proteins/RSGI/2egv TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2egv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2egv OCA], [https://pdbe.org/2egv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2egv RCSB], [https://www.ebi.ac.uk/pdbsum/2egv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2egv ProSAT], [https://www.topsan.org/Proteins/RSGI/2egv TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/RSME_AQUAE RSME_AQUAE]] Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity).  
[[https://www.uniprot.org/uniprot/RSME_AQUAE RSME_AQUAE]] Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity).  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Aquifex aeolicus huber and stetter 2001]]
[[Category: Aquifex aeolicus huber and stetter 2001]]
[[Category: Large Structures]]
[[Category: Bessho, Y]]
[[Category: Bessho, Y]]
[[Category: Dong, X]]
[[Category: Dong, X]]
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