6gpj: Difference between revisions

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'''Unreleased structure'''


The entry 6gpj is ON HOLD
==Crystal structure of human GDP-D-mannose 4,6-dehydratase in complex with GDP-4F-Man==
 
<StructureSection load='6gpj' size='340' side='right' caption='[[6gpj]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
Authors: Pfeiffer, M., Krojer, T., Johansson, C., von Delft, F., Bountra, C., Arrowsmith, C.H., Edwards, A., Nidetzky, B., Oppermann, U., Structural Genomics Consortium (SGC)
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6gpj]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GPJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GPJ FirstGlance]. <br>
Description: Crystal structure of human GDP-D-mannose 4,6-dehydratase in complex with GDP-4F-Man
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=G4F:[[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]+[(2~{R},3~{S},4~{R},5~{S},6~{R})-5-fluoranyl-6-(hydroxymethyl)-3,4-bis(oxidanyl)oxan-2-yl]+hydrogen+phosphate'>G4F</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/GDP-mannose_4,6-dehydratase GDP-mannose 4,6-dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.47 4.2.1.47] </span></td></tr>
[[Category: Pfeiffer, M]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gpj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gpj OCA], [http://pdbe.org/6gpj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gpj RCSB], [http://www.ebi.ac.uk/pdbsum/6gpj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gpj ProSAT]</span></td></tr>
[[Category: Arrowsmith, C.H]]
</table>
== Function ==
[[http://www.uniprot.org/uniprot/GMDS_HUMAN GMDS_HUMAN]] Conversion of GDP-D-mannose to GDP-4-keto-6-D-deoxymannose.
__TOC__
</StructureSection>
[[Category: GDP-mannose 4,6-dehydratase]]
[[Category: Arrowsmith, C H]]
[[Category: Bountra, C]]
[[Category: Delft, F von]]
[[Category: Edwards, A]]
[[Category: Johansson, C]]
[[Category: Johansson, C]]
[[Category: Krojer, T]]
[[Category: Nidetzky, B]]
[[Category: Nidetzky, B]]
[[Category: Oppermann, U]]
[[Category: Oppermann, U]]
[[Category: Structural Genomics Consortium (Sgc)]]
[[Category: Pfeiffer, M]]
[[Category: Edwards, A]]
[[Category: Structural genomic]]
[[Category: Krojer, T]]
[[Category: Dehydratase]]
[[Category: Von Delft, F]]
[[Category: Fucosylation]]
[[Category: Bountra, C]]
[[Category: Gdp-mannose 4]]
[[Category: Lyase]]
[[Category: Sgc]]
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