4zkb: Difference between revisions

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==The chemokine binding protein of orf virus complexed with CCL3==
==The chemokine binding protein of orf virus complexed with CCL3==
<StructureSection load='4zkb' size='340' side='right' caption='[[4zkb]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
<StructureSection load='4zkb' size='340' side='right'caption='[[4zkb]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4zkb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human] and [http://en.wikipedia.org/wiki/Orfn2 Orfn2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZKB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZKB FirstGlance]. <br>
<table><tr><td colspan='2'>[[4zkb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Orf_virus_(strain_NZ2) Orf virus (strain NZ2)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZKB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZKB FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4zk9|4zk9]], [[4zkc|4zkc]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zkb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zkb OCA], [https://pdbe.org/4zkb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zkb RCSB], [https://www.ebi.ac.uk/pdbsum/4zkb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zkb ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CCL3, G0S19-1, MIP1A, SCYA3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zkb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zkb OCA], [http://pdbe.org/4zkb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zkb RCSB], [http://www.ebi.ac.uk/pdbsum/4zkb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4zkb ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CCL3_HUMAN CCL3_HUMAN]] Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).<ref>PMID:8525373</ref> 
[https://www.uniprot.org/uniprot/Q2F862_ORFV Q2F862_ORFV]  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Orfn2]]
[[Category: Large Structures]]
[[Category: Knapp, K M]]
[[Category: Knapp KM]]
[[Category: Krause, K L]]
[[Category: Krause KL]]
[[Category: Nakatani, Y]]
[[Category: Nakatani Y]]
[[Category: Ccl3]]
[[Category: Complex]]
[[Category: Orf chemokine binding protein]]
[[Category: Viral protein-cytokine complex]]
Retrieved from "https://proteopedia.org/4zkb"