6con: Difference between revisions
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==Crystal structure of Mycobacterium tuberculosis IpdAB== | ==Crystal structure of Mycobacterium tuberculosis IpdAB== | ||
<StructureSection load='6con' size='340' side='right' caption='[[6con]], [[Resolution|resolution]] 2.10Å' scene=''> | <StructureSection load='6con' size='340' side='right'caption='[[6con]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6con]] is a 8 chain structure with sequence from [ | <table><tr><td colspan='2'>[[6con]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CON OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CON FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6con FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6con OCA], [https://pdbe.org/6con PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6con RCSB], [https://www.ebi.ac.uk/pdbsum/6con PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6con ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/IPDA_MYCTU IPDA_MYCTU] Involved in the final steps of cholesterol and steroid degradation (PubMed:28377529). Opens the last steroid ring of cholesterol by catalyzing the hydrolysis of (3E)-2-(2-carboxylatoethyl)-3-methyl-6-oxocyclohex-1-ene-1-carboxyl-CoA (COCHEA-CoA) to 6-methyl-3,7-dioxodecanedioyl-CoA (MeDODA-CoA) (PubMed:29581275).<ref>PMID:28377529</ref> <ref>PMID:29581275</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Mycobacterium tuberculosis]] | ||
[[Category: | [[Category: Crowe AM]] | ||
[[Category: | [[Category: Eltis LD]] | ||
[[Category: | [[Category: Strynadka NCJ]] | ||
[[Category: | [[Category: Watanabe N]] | ||
[[Category: | [[Category: Workman SD]] | ||
[[Category: | [[Category: Worrall LJ]] | ||