5z1s: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 5z1s is ~~ON HOLD until Paper Publication~~

==Crystal Structure Analysis of the BRD4(1)==

~~Authors~~: Xu, Y., ~~Zhang~~, Y., ~~Xiang~~, Q., ~~Song~~, M., ~~Wang, C~~.

== Structural highlights ==

<table><tr><td colspan='2'>[[5z1s]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Z1S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5Z1S FirstGlance]. <br>

~~Description~~: ~~Crystal Structure Analysis~~ of ~~the BRD4~~(1)

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EFM:5-bromo-2-methoxy-N-(6-methoxy-2,2-dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)benzene-1-sulfonamide'>EFM</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>

[[~~Category~~: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5z1s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5z1s OCA], [http://pdbe.org/5z1s PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5z1s RCSB], [http://www.ebi.ac.uk/pdbsum/5z1s PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5z1s ProSAT]</span></td></tr>

[[Category: ~~Zhang~~, Y]]

</table>

== Disease ==

[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>

== Function ==

[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).

== References ==

__TOC__

</StructureSection>

[[Category: Song, M]]

[[Category: Wang, C]]

[[Category: Xiang, Q]]

~~[[Category: Song, M]]~~

[[Category: Xu, Y]]

[[Category: Zhang, Y]]

[[Category: Bromodomain]]

[[Category: Transcription]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5z1s is ON HOLD  until Paper Publication
+==Crystal Structure Analysis of the BRD4(1)==
+<StructureSection load='5z1s' size='340' side='right' caption='[[5z1s]], [[Resolution|resolution]] 1.42&Aring;' scene=''>
-Authors: Xu, Y., Zhang, Y., Xiang, Q., Song, M., Wang, C.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5z1s]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5Z1S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5Z1S FirstGlance]. <br>
-Description: Crystal Structure Analysis of the BRD4(1)
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EFM:5-bromo-2-methoxy-N-(6-methoxy-2,2-dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)benzene-1-sulfonamide'>EFM</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5z1s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5z1s OCA], [http://pdbe.org/5z1s PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5z1s RCSB], [http://www.ebi.ac.uk/pdbsum/5z1s PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5z1s ProSAT]</span></td></tr>
-[[Category: Zhang, Y]]
+</table>
+== Disease ==
+[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>
+== Function ==
+[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Song, M]]
 [[Category: Wang, C]]
 [[Category: Xiang, Q]]
-[[Category: Song, M]]
 [[Category: Xu, Y]]
+[[Category: Zhang, Y]]
+[[Category: Bromodomain]]
+[[Category: Transcription]]