6dl7: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6dl7 is ~~ON HOLD until Paper Publication~~

==Human mitochondrial ClpP in complex with ONC201 (TIC10)==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[6dl7]] is a 7 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DL7 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DL7 FirstGlance].

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=ONC:7-benzyl-4-[(2-methylphenyl)methyl]-6,7,8,9-tetrahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(4H)-one'>ONC</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Endopeptidase_Clp Endopeptidase Clp], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.92 3.4.21.92] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dl7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dl7 OCA], [http://pdbe.org/6dl7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dl7 RCSB], [http://www.ebi.ac.uk/pdbsum/6dl7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dl7 ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/CLPP_HUMAN CLPP_HUMAN]] Clp cleaves peptides in various proteins in a process that requires ATP hydrolysis. Clp may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates.

__TOC__

</StructureSection>

[[Category: Endopeptidase Clp]]

[[Category: Large Structures]]

[[Category: Halgas, O]]

[[Category: Pai, E F]]

[[Category: Schimmer, A]]

[[Category: Zarabi, S F]]

[[Category: Degradation]]

[[Category: Homeostasis]]

[[Category: Hydrolase]]

[[Category: Mitochondria]]

[[Category: Protease]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6dl7 is ON HOLD  until Paper Publication
+==Human mitochondrial ClpP in complex with ONC201 (TIC10)==
+<StructureSection load='6dl7' size='340' side='right'caption='[[6dl7]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6dl7]] is a 7 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DL7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DL7 FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ONC:7-benzyl-4-[(2-methylphenyl)methyl]-6,7,8,9-tetrahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(4H)-one'>ONC</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endopeptidase_Clp Endopeptidase Clp], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.92 3.4.21.92] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dl7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dl7 OCA], [http://pdbe.org/6dl7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dl7 RCSB], [http://www.ebi.ac.uk/pdbsum/6dl7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dl7 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/CLPP_HUMAN CLPP_HUMAN]] Clp cleaves peptides in various proteins in a process that requires ATP hydrolysis. Clp may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates.
+__TOC__
+</StructureSection>
+[[Category: Endopeptidase Clp]]
+[[Category: Large Structures]]
+[[Category: Halgas, O]]
+[[Category: Pai, E F]]
+[[Category: Schimmer, A]]
+[[Category: Zarabi, S F]]
+[[Category: Degradation]]
+[[Category: Homeostasis]]
+[[Category: Hydrolase]]
+[[Category: Mitochondria]]
+[[Category: Protease]]