2jh8: Difference between revisions

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[[Image:2jh8.gif|left|200px]]
[[Image:2jh8.gif|left|200px]]


{{Structure
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|SITE= <scene name='pdbsite=AC1:Gun+Binding+Site+For+Chain+A'>AC1</scene>
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|LIGAND= <scene name='pdbligand=GUN:GUANINE'>GUN</scene>, <scene name='pdbligand=M7G:7N-METHYL-8-HYDROGUANOSINE-5&#39;-DIPHOSPHATE'>M7G</scene>
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|DOMAIN=
{{STRUCTURE_2jh8| PDB=2jh8  | SCENE= }}  
|RELATEDENTRY=
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jh8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jh8 OCA], [http://www.ebi.ac.uk/pdbsum/2jh8 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2jh8 RCSB]</span>
}}


'''THE STRUCTURE OF BLUETONGUE VIRUS VP4 REVEALS A MULTIFUNCTIONAL RNA-CAPPING PRODUCTION-LINE'''
'''THE STRUCTURE OF BLUETONGUE VIRUS VP4 REVEALS A MULTIFUNCTIONAL RNA-CAPPING PRODUCTION-LINE'''
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==Reference==
==Reference==
Bluetongue virus VP4 is an RNA-capping assembly line., Sutton G, Grimes JM, Stuart DI, Roy P, Nat Struct Mol Biol. 2007 May;14(5):449-51. Epub 2007 Apr 8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17417654 17417654]
Bluetongue virus VP4 is an RNA-capping assembly line., Sutton G, Grimes JM, Stuart DI, Roy P, Nat Struct Mol Biol. 2007 May;14(5):449-51. Epub 2007 Apr 8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17417654 17417654]
[[Category: Bluetongue virus 10 (isolate usa)]]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Grimes, J M.]]
[[Category: Grimes, J M.]]
Line 29: Line 25:
[[Category: Stuart, D I.]]
[[Category: Stuart, D I.]]
[[Category: Sutton, G.]]
[[Category: Sutton, G.]]
[[Category: core protein]]
[[Category: Core protein]]
[[Category: guanylyltransferase]]
[[Category: Guanylyltransferase]]
[[Category: methyltransferase]]
[[Category: Methyltransferase]]
[[Category: viral capping enzyme]]
[[Category: Viral capping enzyme]]
[[Category: viral protein]]
[[Category: Viral protein]]
[[Category: virion protein]]
[[Category: Virion protein]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May  4 08:54:56 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:58:09 2008''

Revision as of 05:54, 4 May 2008

File:2jh8.gif

Template:STRUCTURE 2jh8

THE STRUCTURE OF BLUETONGUE VIRUS VP4 REVEALS A MULTIFUNCTIONAL RNA-CAPPING PRODUCTION-LINE


Overview

Eukaryotic organisms cap the 5' ends of their messenger RNAs by a series of four chemical reactions. Some viruses achieve this using a single molecule; the crystal structure of such an enzyme from bluetongue virus reveals an elongated modular architecture that provides a scaffold for an assemblage of active sites, two contributed by a domain of novel structure.

About this Structure

2JH8 is a Single protein structure of sequence from Bluetongue virus 10 (isolate usa). Full crystallographic information is available from OCA.

Reference

Bluetongue virus VP4 is an RNA-capping assembly line., Sutton G, Grimes JM, Stuart DI, Roy P, Nat Struct Mol Biol. 2007 May;14(5):449-51. Epub 2007 Apr 8. PMID:17417654 Page seeded by OCA on Sun May 4 08:54:56 2008

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