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==Crystal structure of yellow lupin LLPR-10.2B protein in complex with melatonin and trans-zeatin.==
==Crystal structure of yellow lupin LLPR-10.2B protein in complex with melatonin and trans-zeatin.==
<StructureSection load='5mxw' size='340' side='right' caption='[[5mxw]], [[Resolution|resolution]] 1.57&Aring;' scene=''>
<StructureSection load='5mxw' size='340' side='right'caption='[[5mxw]], [[Resolution|resolution]] 1.57&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5mxw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/European_yellow_lupine European yellow lupine]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MXW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MXW FirstGlance]. <br>
<table><tr><td colspan='2'>[[5mxw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lupinus_luteus Lupinus luteus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MXW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MXW FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ML1:N-[2-(5-METHOXY-1H-INDOL-3-YL)ETHYL]ACETAMIDE'>ML1</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene>, <scene name='pdbligand=ZEA:(2E)-2-METHYL-4-(9H-PURIN-6-YLAMINO)BUT-2-EN-1-OL'>ZEA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.57&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5mxb|5mxb]], [[5c9y|5c9y]], [[4ryv|4ryv]], [[4y31|4y31]], [[4n3e|4n3e]], [[4psb|4psb]], [[4q0k|4q0k]], [[4jhh|4jhh]], [[4jhi|4jhi]], [[4jhg|4jhg]], [[4gy9|4gy9]], [[3ie5|3ie5]], [[3e85|3e85]], [[2qim|2qim]], [[2flh|2flh]], [[1xdf|1xdf]], [[1icx|1icx]], [[1ifv|1ifv]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ML1:N-[2-(5-METHOXY-1H-INDOL-3-YL)ETHYL]ACETAMIDE'>ML1</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene>, <scene name='pdbligand=ZEA:(2E)-2-METHYL-4-(9H-PURIN-6-YLAMINO)BUT-2-EN-1-OL'>ZEA</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pr10.2b, Ypr10.2b ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3873 European yellow lupine])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5mxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mxw OCA], [https://pdbe.org/5mxw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5mxw RCSB], [https://www.ebi.ac.uk/pdbsum/5mxw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5mxw ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mxw OCA], [http://pdbe.org/5mxw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mxw RCSB], [http://www.ebi.ac.uk/pdbsum/5mxw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mxw ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/P102B_LUPLU P102B_LUPLU] Class II ribonuclease (RNase) (By similarity). Binds to several cytokinins including natural adenine-type (e.g. trans-zeatin and kinetin) and artificial urea-type (e.g. N,N'-diphenylurea and N-phenyl-N'-(2-chloro-4-pyridyl)urea) hormones (PubMed:18406424, PubMed:19220853, PubMed:29630775). Interacts with melatonin (PubMed:29630775).[UniProtKB:P52779]<ref>PMID:18406424</ref> <ref>PMID:19220853</ref> <ref>PMID:29630775</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: European yellow lupine]]
[[Category: Large Structures]]
[[Category: Jaskolski, M]]
[[Category: Lupinus luteus]]
[[Category: Sikorski, M]]
[[Category: Jaskolski M]]
[[Category: Sliwiak, J]]
[[Category: Sikorski M]]
[[Category: Melatonin]]
[[Category: Sliwiak J]]
[[Category: Phytohormon binding protein]]
[[Category: Plant protein]]
[[Category: Pr-10 protein]]
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