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==Crystal structure of Medicago truncatula serine hydroxymethyltransferase 3 (MtSHMT3), PLP-internal aldimine and apo form==
==Crystal structure of Medicago truncatula serine hydroxymethyltransferase 3 (MtSHMT3), PLP-internal aldimine and apo form==
<StructureSection load='6cd0' size='340' side='right' caption='[[6cd0]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
<StructureSection load='6cd0' size='340' side='right'caption='[[6cd0]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6cd0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Barrel_medic Barrel medic]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CD0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6CD0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[6cd0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Medicago_truncatula Medicago truncatula]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6CD0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6CD0 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.74&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">11445860, MTR_2g018290 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3880 Barrel medic])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6cd0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cd0 OCA], [https://pdbe.org/6cd0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6cd0 RCSB], [https://www.ebi.ac.uk/pdbsum/6cd0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6cd0 ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glycine_hydroxymethyltransferase Glycine hydroxymethyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.2.1 2.1.2.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6cd0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6cd0 OCA], [http://pdbe.org/6cd0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6cd0 RCSB], [http://www.ebi.ac.uk/pdbsum/6cd0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6cd0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/G7ILW0_MEDTR G7ILW0_MEDTR]] Interconversion of serine and glycine.[RuleBase:RU000585]  
[https://www.uniprot.org/uniprot/G7ILW0_MEDTR G7ILW0_MEDTR] Interconversion of serine and glycine.[RuleBase:RU000585]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6cd0" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6cd0" style="background-color:#fffaf0;"></div>
==See Also==
*[[Serine hydroxymethyltransferase 3D structures|Serine hydroxymethyltransferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Barrel medic]]
[[Category: Large Structures]]
[[Category: Glycine hydroxymethyltransferase]]
[[Category: Medicago truncatula]]
[[Category: Dauter, Z]]
[[Category: Dauter Z]]
[[Category: Ruszkowska, A]]
[[Category: Ruszkowska A]]
[[Category: Ruszkowski, M]]
[[Category: Ruszkowski M]]
[[Category: Sekula, B]]
[[Category: Sekula B]]
[[Category: Chloroplast]]
[[Category: One-carbon cycle]]
[[Category: Plp]]
[[Category: Tetrahydrofolate]]
[[Category: Tetramer]]
[[Category: Transferase]]

Latest revision as of 15:01, 4 October 2023

Crystal structure of Medicago truncatula serine hydroxymethyltransferase 3 (MtSHMT3), PLP-internal aldimine and apo form

6cd0, resolution 1.74Å

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