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==Complex of TM1a(1-14)Zip with TM9a(251-284): a model for the polymerization domain ("overlap region") of tropomyosin, Northeast Structural Genomics Target OR9==
==Complex of TM1a(1-14)Zip with TM9a(251-284): a model for the polymerization domain ("overlap region") of tropomyosin, Northeast Structural Genomics Target OR9==
<StructureSection load='2g9j' size='340' side='right' caption='[[2g9j]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
<StructureSection load='2g9j' size='340' side='right'caption='[[2g9j]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2g9j]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G9J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2G9J FirstGlance]. <br>
<table><tr><td colspan='2'>[[2g9j]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G9J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2G9J FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1tmz|1tmz]], [[1mv4|1mv4]]</td></tr>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1tmz|1tmz]], [[1mv4|1mv4]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TPM1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TPM1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2g9j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g9j OCA], [http://pdbe.org/2g9j PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2g9j RCSB], [http://www.ebi.ac.uk/pdbsum/2g9j PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2g9j ProSAT], [http://www.topsan.org/Proteins/NESGC/2g9j TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2g9j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2g9j OCA], [https://pdbe.org/2g9j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2g9j RCSB], [https://www.ebi.ac.uk/pdbsum/2g9j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2g9j ProSAT], [https://www.topsan.org/Proteins/NESGC/2g9j TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/TPM1_RAT TPM1_RAT]] Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.  
[[https://www.uniprot.org/uniprot/TPM1_RAT TPM1_RAT]] Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments.  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Gcn4|Gcn4]]
*[[Gnc4 3D Structures|Gnc4 3D Structures]]
*[[Tropomyosin|Tropomyosin]]
*[[Tropomyosin|Tropomyosin]]
== References ==
== References ==
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</StructureSection>
</StructureSection>
[[Category: Buffalo rat]]
[[Category: Buffalo rat]]
[[Category: Large Structures]]
[[Category: Bhattacharya, A]]
[[Category: Bhattacharya, A]]
[[Category: Greenfield, N J]]
[[Category: Greenfield, N J]]
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