6gso: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6gso is ~~ON HOLD until Paper Publication~~

==Sulfolobus solfataricus 2-keto-3-deoxygluconate aldolase Y132V,T157C variant==

~~Authors~~: ~~Crennell~~, S.J., ~~Danson~~, M.J., ~~Royer~~, S.

== Structural highlights ==

<table><tr><td colspan='2'>[[6gso]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GSO OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GSO FirstGlance].

~~Description~~: ~~Sulfolobus solfataricus~~ 2-keto-3-deoxygluconate aldolase ~~Y132V,T157C variant~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[2yda|2yda]]</td></tr>

[[Category: Crennell, S.J]]

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate_aldolase 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.55 4.1.2.55] </td></tr>

[[Category: Danson, M.J]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gso OCA], [http://pdbe.org/6gso PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gso RCSB], [http://www.ebi.ac.uk/pdbsum/6gso PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gso ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/KDGA_SULSF KDGA_SULSF]] Involved in the degradation of glucose and galactose via the Entner-Doudoroff pathway. Catalyzes the reversible cleavage of 2-keto-3-deoxy-6-phosphogluconate (KDPG) and 2-keto-3-deoxygluconate (KDG) forming pyruvate and glyceraldehyde 3-phosphate or glyceraldehyde, respectively. It is also able to catalyze the reversible cleavage of 2-keto-3-deoxy-6-phosphogalactonate (KDPGal) and 2-keto-3-deoxygalactonate (KDGal). It is equally active with both D- and L-glyceraldehyde.<ref>PMID:10527934</ref> <ref>PMID:12824170</ref> <ref>PMID:16330030</ref>

== References ==

__TOC__

</StructureSection>

[[Category: 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase]]

[[Category: Large Structures]]

[[Category: Crennell, S J]]

[[Category: Danson, M J]]

[[Category: Royer, S]]

[[Category: 2-keto-3-deoxygluconate]]

[[Category: Aldolase]]

[[Category: Hydrolase]]

[[Category: Sulfolobus solfataricus]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6gso is ON HOLD  until Paper Publication
+==Sulfolobus solfataricus 2-keto-3-deoxygluconate aldolase Y132V,T157C variant==
+<StructureSection load='6gso' size='340' side='right'caption='[[6gso]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-Authors: Crennell, S.J., Danson, M.J., Royer, S.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6gso]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GSO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GSO FirstGlance]. <br>
-Description: Sulfolobus solfataricus 2-keto-3-deoxygluconate aldolase Y132V,T157C variant
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2yda|2yda]]</td></tr>
-[[Category: Crennell, S.J]]
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate_aldolase 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.55 4.1.2.55] </span></td></tr>
-[[Category: Danson, M.J]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gso OCA], [http://pdbe.org/6gso PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gso RCSB], [http://www.ebi.ac.uk/pdbsum/6gso PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gso ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/KDGA_SULSF KDGA_SULSF]] Involved in the degradation of glucose and galactose via the Entner-Doudoroff pathway. Catalyzes the reversible cleavage of 2-keto-3-deoxy-6-phosphogluconate (KDPG) and 2-keto-3-deoxygluconate (KDG) forming pyruvate and glyceraldehyde 3-phosphate or glyceraldehyde, respectively. It is also able to catalyze the reversible cleavage of 2-keto-3-deoxy-6-phosphogalactonate (KDPGal) and 2-keto-3-deoxygalactonate (KDGal). It is equally active with both D- and L-glyceraldehyde.<ref>PMID:10527934</ref> <ref>PMID:12824170</ref> <ref>PMID:16330030</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase]]
+[[Category: Large Structures]]
+[[Category: Crennell, S J]]
+[[Category: Danson, M J]]
 [[Category: Royer, S]]
+[[Category: 2-keto-3-deoxygluconate]]
+[[Category: Aldolase]]
+[[Category: Hydrolase]]
+[[Category: Sulfolobus solfataricus]]