5o97: Difference between revisions

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==Crystal structure of human BRD4(1) bromodomain in complex with JRMBR4106==
==Crystal structure of human BRD4(1) bromodomain in complex with JRMBR4106==
<StructureSection load='5o97' size='340' side='right' caption='[[5o97]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
<StructureSection load='5o97' size='340' side='right'caption='[[5o97]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5o97]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5O97 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5O97 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5o97]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5O97 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5O97 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9OE:(5~{Z})-4-azanyl-5-[(3-methoxy-4-oxidanyl-phenyl)methylidene]-1,3-thiazol-2-one'>9OE</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9OE:(5~{Z})-4-azanyl-5-[(3-methoxy-4-oxidanyl-phenyl)methylidene]-1,3-thiazol-2-one'>9OE</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5o97 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5o97 OCA], [http://pdbe.org/5o97 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5o97 RCSB], [http://www.ebi.ac.uk/pdbsum/5o97 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5o97 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5o97 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5o97 OCA], [http://pdbe.org/5o97 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5o97 RCSB], [http://www.ebi.ac.uk/pdbsum/5o97 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5o97 ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).  
[[http://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN]] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).  
==See Also==
*[[Bromodomain-containing protein 3D structures|Bromodomain-containing protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Caflisch, A]]
[[Category: Caflisch, A]]
[[Category: Marchand, J R]]
[[Category: Marchand, J R]]