6dja: Difference between revisions
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==ZN-DEPENDENT 5/B/6 METALLO-BETA-LACTAMASE FROM BACILLUS CEREUS== | |||
<StructureSection load='6dja' size='340' side='right'caption='[[6dja]], [[Resolution|resolution]] 2.48Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6dja]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DJA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6DJA FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6dja FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dja OCA], [http://pdbe.org/6dja PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6dja RCSB], [http://www.ebi.ac.uk/pdbsum/6dja PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6dja ProSAT]</span></td></tr> | ||
[[Category: Bui, A | </table> | ||
[[Category: Khan, N | == Function == | ||
[[Category: Shaw, R | [[http://www.uniprot.org/uniprot/BLAB_BACCE BLAB_BACCE]] Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring. Benzylpenicillin is a better substrate than cephalosporin C and ampicillin (PubMed:3131315, PubMed:2501295).<ref>PMID:1904717</ref> <ref>PMID:2501295</ref> <ref>PMID:3131315</ref> | ||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Beta-lactamase]] | |||
[[Category: Large Structures]] | |||
[[Category: Bui, A A]] | |||
[[Category: Khan, N H]] | |||
[[Category: Shaw, R W]] | |||
[[Category: Sutton, R B]] | |||
[[Category: Hydrolase]] | |||
[[Category: Lactamase]] | |||
[[Category: Zinc]] | |||
Revision as of 06:04, 29 May 2019
ZN-DEPENDENT 5/B/6 METALLO-BETA-LACTAMASE FROM BACILLUS CEREUS
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