2jv9: Difference between revisions
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==The Solution Structure of Calponin Homology Domain from Smoothelin-like 1== | ==The Solution Structure of Calponin Homology Domain from Smoothelin-like 1== | ||
<StructureSection load='2jv9' size='340' side='right' caption='[[2jv9]], [[NMR_Ensembles_of_Models | 30 NMR models]]' scene=''> | <StructureSection load='2jv9' size='340' side='right'caption='[[2jv9]], [[NMR_Ensembles_of_Models | 30 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2jv9]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2jv9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JV9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JV9 FirstGlance]. <br> | ||
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Smtnl1, RP23-399J8.5 ([ | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Smtnl1, RP23-399J8.5 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jv9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jv9 OCA], [https://pdbe.org/2jv9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jv9 RCSB], [https://www.ebi.ac.uk/pdbsum/2jv9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jv9 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/SMTL1_MOUSE SMTL1_MOUSE]] Plays a role in the regulation of contractile properties of both striated and smooth muscles. When unphosphorylated, may inhibit myosin dephosphorylation. Phosphorylation at Ser-301 reduces this inhibitory activity.<ref>PMID:18310078</ref> <ref>PMID:20634291</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Ishida, H]] | [[Category: Ishida, H]] | ||