Electron density maps: Difference between revisions
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==Why Look At Electron Density Maps?== | ==Why Look At Electron Density Maps?== | ||
Examining the correspondence between the published model [[PDB file]] and the electron density map (EDM) provides much clearer insight into the uncertainties in the model than does merely examining the model itself (see also | Examining the correspondence between the published model [[PDB file]] and the electron density map (EDM) provides much clearer insight into the uncertainties in the model than does merely examining the model itself<ref name="silvaggi">PMID 25554228</ref> (see also | ||
[[Quality assessment for molecular models]]). In addition to examining the entire map (2mFo-DFc) it is revealing to examine the ''difference map'' (mFo-DFc), which shows where the model fails to account for the map. | [[Quality assessment for molecular models]]). In addition to examining the entire map (2mFo-DFc) it is revealing to examine the ''difference map'' (mFo-DFc), which shows where the model fails to account for the map. | ||