6gs6: Difference between revisions
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==Cyclophilin A single mutant D66A in complex with an inhibitor.== | |||
<StructureSection load='6gs6' size='340' side='right'caption='[[6gs6]], [[Resolution|resolution]] 1.16Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6gs6]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6GS6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6GS6 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EA4:ETHYL+N-[(4-AMINOBENZYL)CARBAMOYL]GLYCINATE'>EA4</scene></td></tr> | |||
[[Category: | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6gs6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6gs6 OCA], [http://pdbe.org/6gs6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6gs6 RCSB], [http://www.ebi.ac.uk/pdbsum/6gs6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6gs6 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/PPIA_HUMAN PPIA_HUMAN]] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Peptidylprolyl isomerase]] | |||
[[Category: Georgiou, C]] | |||
[[Category: Juarez-Jimenez, J]] | [[Category: Juarez-Jimenez, J]] | ||
[[Category: Michel, J]] | [[Category: Michel, J]] | ||
[[Category: | [[Category: Simone, A De]] | ||
[[Category: Walkinshaw, M | [[Category: Walkinshaw, M D]] | ||
[[Category: Complex]] | |||
[[Category: Cyclophilin]] | |||
[[Category: Cypa]] | |||
[[Category: Cypa mutant]] | |||
[[Category: Inhibitor]] | |||
[[Category: Isomerase]] | |||
[[Category: Ppiase]] | |||
Revision as of 06:46, 26 June 2019
Cyclophilin A single mutant D66A in complex with an inhibitor.
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