6e18: Difference between revisions

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'''Unreleased structure'''


The entry 6e18 is ON HOLD until Jul 09 2020
==Crystal structure of Chlamydomonas reinhardtii HAP2 ectodomain provides structural insights of functional loops in green algae.==
 
<StructureSection load='6e18' size='340' side='right' caption='[[6e18]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6e18]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6E18 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6E18 FirstGlance]. <br>
Description:  
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6e18 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6e18 OCA], [http://pdbe.org/6e18 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6e18 RCSB], [http://www.ebi.ac.uk/pdbsum/6e18 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6e18 ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/HAP2_CHLRE HAP2_CHLRE]] During fertilization, required on male (minus) gametes for their fusion with female (plus) gametes (PubMed:18367645, PubMed:20335357, PubMed:25655701, PubMed:28235200). Required for membrane fusion, but not for the initial adhesion between gametes (PubMed:18367645, PubMed:25655701, PubMed:28235200). Inserts (via its extracellular domain) into lipid membranes (in vitro) (PubMed:28235200). Probably initiates the fusion of gamete cell membranes by inserting its extracellular domain into the cell membrane of a female gamete (PubMed:28235200).<ref>PMID:18367645</ref> <ref>PMID:20335357</ref> <ref>PMID:25655701</ref> <ref>PMID:28235200</ref>  
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Baquero, E]]
[[Category: Legrand, P]]
[[Category: Rey, F A]]
[[Category: Cystine ladder]]
[[Category: Gamete fusion]]
[[Category: Glycoprotein]]
[[Category: Membrane binding motif]]
[[Category: Membrane protein]]
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