2lm1: Difference between revisions
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==Solution NMR Structure of Lysine-specific demethylase lid from Drosophila melanogaster, Northeast Structural Genomics Consortium Target FR824D== | ==Solution NMR Structure of Lysine-specific demethylase lid from Drosophila melanogaster, Northeast Structural Genomics Consortium Target FR824D== | ||
<StructureSection load='2lm1' size='340' side='right' caption='[[2lm1]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | <StructureSection load='2lm1' size='340' side='right'caption='[[2lm1]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2lm1]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2lm1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drome Drome]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LM1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LM1 FirstGlance]. <br> | ||
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CG9088, lid ([ | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CG9088, lid ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lm1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lm1 OCA], [https://pdbe.org/2lm1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lm1 RCSB], [https://www.ebi.ac.uk/pdbsum/2lm1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lm1 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/KDM5_DROME KDM5_DROME]] Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Specifically demethylates trimethylated H3 'Lys-4'. Required for the correct regulation of homeotic genes during development.<ref>PMID:11014813</ref> <ref>PMID:17311883</ref> <ref>PMID:17351631</ref> <ref>PMID:17351630</ref> | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Drome]] | [[Category: Drome]] | ||
[[Category: Large Structures]] | |||
[[Category: Acton, T B]] | [[Category: Acton, T B]] | ||
[[Category: CEBS, Chaperone-Enabled Studies of Epigenetic Regulation Enzymes]] | [[Category: CEBS, Chaperone-Enabled Studies of Epigenetic Regulation Enzymes]] | ||
Revision as of 10:13, 12 May 2021
Solution NMR Structure of Lysine-specific demethylase lid from Drosophila melanogaster, Northeast Structural Genomics Consortium Target FR824D
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Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Drome
- Large Structures
- Acton, T B
- CEBS, Chaperone-Enabled Studies of Epigenetic Regulation Enzymes
- Everett, J K
- Kohan, E
- Kusch, T
- Lee, D
- Mills, J L
- Montelione, G T
- Structural genomic
- Sahdev, S
- Szyperski, T
- Xiao, R
- Ceb
- Chaperone-enabled studies of epigenetic regulation enzyme
- Dna binding protein
- PSI, Protein structure initiative
- Psi-biology
