Introduction to Evolutionary Conservation: Difference between revisions
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==Expected vs. Unexpected Conservation== | ==Expected vs. Unexpected Conservation== | ||
Conservation is '''expected''' for those amino acids that support the 3D structure and functions of a protein. Common examples are listed in the table below. When there is no known structural or functional explanation for conservation of an amino acid, or a cluster of amino acids, | Conservation is '''expected''' for those amino acids that support the 3D structure and functions of a protein. Common examples are listed in the table below. When there is no known structural or functional explanation for conservation of an amino acid, or a cluster of amino acids, the conservation is '''unexpected'''. Unexpected conservation may provide clues for discovering new functions or structural features, e.g. through functional analysis of mutants. | ||
<table class="wikitable"><tr> | <table class="wikitable"><tr> | ||
