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==Solution structure of CXC domain of MSL2==
==Solution structure of CXC domain of MSL2==
<StructureSection load='2lua' size='340' side='right' caption='[[2lua]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2lua' size='340' side='right'caption='[[2lua]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2lua]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LUA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LUA FirstGlance]. <br>
<table><tr><td colspan='2'>[[2lua]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drome Drome]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LUA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LUA FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">msl-2, CG3241 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">msl-2, CG3241 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lua OCA], [http://pdbe.org/2lua PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lua RCSB], [http://www.ebi.ac.uk/pdbsum/2lua PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2lua ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lua FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lua OCA], [https://pdbe.org/2lua PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lua RCSB], [https://www.ebi.ac.uk/pdbsum/2lua PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lua ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MSL2_DROME MSL2_DROME]] The Msl proteins are essential for elevating transcription of the single X chromosome in the male (X chromosome dosage compensation). Msl-2 is required for translation and/or stability of msl-1 in males. In complex with msl-1, acts as an E3 ubiquitin ligase that promotes ubiquitination of histone H2B.<ref>PMID:21726816</ref> <ref>PMID:7588059</ref> <ref>PMID:7781064</ref> <ref>PMID:7796814</ref>   
[[https://www.uniprot.org/uniprot/MSL2_DROME MSL2_DROME]] The Msl proteins are essential for elevating transcription of the single X chromosome in the male (X chromosome dosage compensation). Msl-2 is required for translation and/or stability of msl-1 in males. In complex with msl-1, acts as an E3 ubiquitin ligase that promotes ubiquitination of histone H2B.<ref>PMID:21726816</ref> <ref>PMID:7588059</ref> <ref>PMID:7781064</ref> <ref>PMID:7796814</ref>   
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Drome]]
[[Category: Drome]]
[[Category: Large Structures]]
[[Category: Feng, Y]]
[[Category: Feng, Y]]
[[Category: Wang, J]]
[[Category: Wang, J]]
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