5qij: Difference between revisions

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~~'''Unreleased structure'''~~

~~The entry 5qij is ON HOLD until Paper Publication~~

==CRYSTAL STRUCTURE OF MURINE 11B- HYDROXYSTEROIDDEHYDROGENASE COMPLEXED WITH 2-(3-(1-(4- CHLOROPHENYL)CYCLOPROPYL)-[1,2,4]TRIAZOLO[4,3-A]PYRIDIN-8- YL)PROPAN-2-OL==

~~Authors: Sheriff, S.~~

== Structural highlights ==

<table><tr><td colspan='2'>[[5qij]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QIJ OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5QIJ FirstGlance].

~~Description:~~ CRYSTAL STRUCTURE OF MURINE 11B-HYDROXYSTEROIDDEHYDROGENASE COMPLEXED WITH 2-(3-(1-(4-CHLOROPHENYL)CYCLOPROPYL)-[1,2,4]TRIAZOLO[4,3-A]PYRIDIN-8-YL)PROPAN-2-OL

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=HJG:2-{3-[1-(4-chlorophenyl)cyclopropyl][1,2,4]triazolo[4,3-a]pyridin-8-yl}propan-2-ol'>HJG</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/11-beta-hydroxysteroid_dehydrogenase 11-beta-hydroxysteroid dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.146 1.1.1.146] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5qij FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qij OCA], [http://pdbe.org/5qij PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qij RCSB], [http://www.ebi.ac.uk/pdbsum/5qij PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qij ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/DHI1_MOUSE DHI1_MOUSE]] Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone.

__TOC__

</StructureSection>

[[Category: 11-beta-hydroxysteroid dehydrogenase]]

[[Category: Sheriff, S]]

[[Category: 11b-hsd1]]

[[Category: Dehydrogenase]]

[[Category: Hydroxysteroid]]

[[Category: Inhibitor]]

[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]

[[Category: Sdr]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 5qij is ON HOLD  until Paper Publication
+==CRYSTAL STRUCTURE OF MURINE 11B- HYDROXYSTEROIDDEHYDROGENASE COMPLEXED WITH 2-(3-(1-(4- CHLOROPHENYL)CYCLOPROPYL)-[1,2,4]TRIAZOLO[4,3-A]PYRIDIN-8- YL)PROPAN-2-OL==
+<StructureSection load='5qij' size='340' side='right' caption='[[5qij]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
-Authors: Sheriff, S.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5qij]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QIJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5QIJ FirstGlance]. <br>
-Description: CRYSTAL STRUCTURE OF MURINE 11B-HYDROXYSTEROIDDEHYDROGENASE COMPLEXED WITH 2-(3-(1-(4-CHLOROPHENYL)CYCLOPROPYL)-[1,2,4]TRIAZOLO[4,3-A]PYRIDIN-8-YL)PROPAN-2-OL
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HJG:2-{3-[1-(4-chlorophenyl)cyclopropyl][1,2,4]triazolo[4,3-a]pyridin-8-yl}propan-2-ol'>HJG</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/11-beta-hydroxysteroid_dehydrogenase 11-beta-hydroxysteroid dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.146 1.1.1.146] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5qij FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qij OCA], [http://pdbe.org/5qij PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5qij RCSB], [http://www.ebi.ac.uk/pdbsum/5qij PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5qij ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/DHI1_MOUSE DHI1_MOUSE]] Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone.
+__TOC__
+</StructureSection>
+[[Category: 11-beta-hydroxysteroid dehydrogenase]]
 [[Category: Sheriff, S]]
+[[Category: 11b-hsd1]]
+[[Category: Dehydrogenase]]
+[[Category: Hydroxysteroid]]
+[[Category: Inhibitor]]
+[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
+[[Category: Sdr]]