6e48: Difference between revisions
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==Crystal Structure of the Murine Norovirus VP1 P domain in complex with the CD300lf Receptor and Lithocholic Acid== | |||
<StructureSection load='6e48' size='340' side='right' caption='[[6e48]], [[Resolution|resolution]] 1.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6e48]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6E48 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6E48 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4OA:(3BETA,5BETA,14BETA,17ALPHA)-3-HYDROXYCHOLAN-24-OIC+ACID'>4OA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | |||
[[ | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3lq6|3lq6]]</td></tr> | ||
[[Category: Fremont, D | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6e48 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6e48 OCA], [http://pdbe.org/6e48 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6e48 RCSB], [http://www.ebi.ac.uk/pdbsum/6e48 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6e48 ProSAT]</span></td></tr> | ||
[[Category: Nelson, C | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/CLM1_MOUSE CLM1_MOUSE]] Acts as an inhibitory receptor for myeloid cells and mast cells. Inhibits osteoclast formation. Induces macrophage cell death upon engagement.<ref>PMID:14662855</ref> <ref>PMID:17438331</ref> <ref>PMID:18097021</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Fremont, D H]] | |||
[[Category: Nelson, C A]] | |||
[[Category: Bile acid]] | |||
[[Category: Capsid protein]] | |||
[[Category: Clm-1]] | |||
[[Category: Clm1]] | |||
[[Category: Cmrf-35-like molecule-1]] | |||
[[Category: Dir2]] | |||
[[Category: Igsf13]] | |||
[[Category: Irem1]] | |||
[[Category: Lca]] | |||
[[Category: Lmir3]] | |||
[[Category: Myeloid receptor]] | |||
[[Category: Norovirus]] | |||
[[Category: Pigr3]] | |||
[[Category: Protruding domain]] | |||
[[Category: Viral protein]] | |||
Revision as of 07:37, 12 September 2018
Crystal Structure of the Murine Norovirus VP1 P domain in complex with the CD300lf Receptor and Lithocholic Acid
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