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==The structure of the type III effector AvrB complexed with a high-affinity RIN4 peptide==
==The structure of the type III effector AvrB complexed with a high-affinity RIN4 peptide==
<StructureSection load='2nud' size='340' side='right' caption='[[2nud]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='2nud' size='340' side='right'caption='[[2nud]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2nud]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Psesg Psesg]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NUD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2NUD FirstGlance]. <br>
<table><tr><td colspan='2'>[[2nud]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Psesg Psesg]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NUD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NUD FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ETF:TRIFLUOROETHANOL'>ETF</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ETF:TRIFLUOROETHANOL'>ETF</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1nh1|1nh1]], [[2nun|2nun]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1nh1|1nh1]], [[2nun|2nun]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">avrB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=318 PSESG])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">avrB ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=318 PSESG])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2nud FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nud OCA], [http://pdbe.org/2nud PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2nud RCSB], [http://www.ebi.ac.uk/pdbsum/2nud PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2nud ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nud FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nud OCA], [https://pdbe.org/2nud PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nud RCSB], [https://www.ebi.ac.uk/pdbsum/2nud PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nud ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/RIN4_ARATH RIN4_ARATH]] Essential regulator of plant defense, which plays a central role in resistance in case of infection by a pathogen. It is a common target for both type III avirulence proteins from P.syringae (AvrB, AvrRpm1 and AvrRpt2) and for the plant Resistance (R) proteins RPM1 and RPS2. In strains carrying the appropriate R gene for avirulence proteins of the pathogen, its association with avirulence proteins triggers a defense system including the hypersensitive response, which limits the spread of disease. In contrast, in plants lacking appropriate R genes, its association with avirulence proteins of the pathogen impairs the defense system and leads to the pathogen multiplication.<ref>PMID:11955429</ref> <ref>PMID:12581526</ref> <ref>PMID:12581527</ref>   
[[https://www.uniprot.org/uniprot/RIN4_ARATH RIN4_ARATH]] Essential regulator of plant defense, which plays a central role in resistance in case of infection by a pathogen. It is a common target for both type III avirulence proteins from P.syringae (AvrB, AvrRpm1 and AvrRpt2) and for the plant Resistance (R) proteins RPM1 and RPS2. In strains carrying the appropriate R gene for avirulence proteins of the pathogen, its association with avirulence proteins triggers a defense system including the hypersensitive response, which limits the spread of disease. In contrast, in plants lacking appropriate R genes, its association with avirulence proteins of the pathogen impairs the defense system and leads to the pathogen multiplication.<ref>PMID:11955429</ref> <ref>PMID:12581526</ref> <ref>PMID:12581527</ref>   
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Avirulence protein|Avirulence protein]]
*[[Avirulence protein 3D structures|Avirulence protein 3D structures]]
*[[Type III effector AvrB complexed with a high-affinity RIN4 peptide|Type III effector AvrB complexed with a high-affinity RIN4 peptide]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Psesg]]
[[Category: Psesg]]
[[Category: Dangl, J L]]
[[Category: Dangl, J L]]
Retrieved from "https://proteopedia.org/2nud"