Plasminogen: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<scene name='46/465445/Cv/ | <scene name='46/465445/Cv/11'>PLN contains 7 domains</scene> which are: N-terminal, C-terminal serine protease catalytic domain and 5 kringle domains of ca. 80 residues. The <scene name='46/465445/Cv/3'>kringle domain folds into a large loop containing 3 disulfide bonds</scene>, ''e.g.'' <scene name='46/465445/Cv/4'>Kringle 4</scene>. The kringle domain is important in protein-protein interaction with blood coagulation factors.<ref>PMID:22832192</ref>. | ||
*<scene name='46/465445/Cv/ | *<scene name='46/465445/Cv/12'>K ion coordination site</scene>. Water molecules are shown as red spheres. | ||
*<scene name='46/465445/Cv/ | *<scene name='46/465445/Cv/13'>Cl ion coordination site I</scene>. | ||
*<scene name='46/465445/Cv/8'>Cl ion coordination site II</scene>. | *<scene name='46/465445/Cv/8'>Cl ion coordination site II</scene>. | ||
*<scene name='46/465445/Cv/9'>Cl ion coordination site III</scene>. | *<scene name='46/465445/Cv/9'>Cl ion coordination site III</scene>. | ||
