2qnf: Difference between revisions

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==Crystal structure of T4 Endonuclease VII H43N mutant in complex with heteroduplex DNA containing base mismatches==
==Crystal structure of T4 Endonuclease VII H43N mutant in complex with heteroduplex DNA containing base mismatches==
<StructureSection load='2qnf' size='340' side='right' caption='[[2qnf]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
<StructureSection load='2qnf' size='340' side='right'caption='[[2qnf]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2qnf]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpt4 Bpt4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QNF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QNF FirstGlance]. <br>
<table><tr><td colspan='2'>[[2qnf]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bpt4 Bpt4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QNF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QNF FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1e7d|1e7d]], [[1e7l|1e7l]], [[1en7|1en7]], [[2qnc|2qnc]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1e7d|1e7d]], [[1e7l|1e7l]], [[1en7|1en7]], [[2qnc|2qnc]]</div></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">49 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 BPT4])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">49 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10665 BPT4])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Crossover_junction_endodeoxyribonuclease Crossover junction endodeoxyribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.22.4 3.1.22.4] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Crossover_junction_endodeoxyribonuclease Crossover junction endodeoxyribonuclease], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.22.4 3.1.22.4] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qnf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qnf OCA], [http://pdbe.org/2qnf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2qnf RCSB], [http://www.ebi.ac.uk/pdbsum/2qnf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2qnf ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qnf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qnf OCA], [https://pdbe.org/2qnf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qnf RCSB], [https://www.ebi.ac.uk/pdbsum/2qnf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qnf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/END7_BPT4 END7_BPT4]] Cleaves DNA cruciform and Y-structures as well as heteroduplex loops. Resolves Holliday junctions, recognizes a broad spectrum of DNA substrates ranging from branched DNAs to single base mismatches.  
[[https://www.uniprot.org/uniprot/END7_BPT4 END7_BPT4]] Cleaves DNA cruciform and Y-structures as well as heteroduplex loops. Resolves Holliday junctions, recognizes a broad spectrum of DNA substrates ranging from branched DNAs to single base mismatches.  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Endonuclease|Endonuclease]]
*[[Endonuclease 3D structures|Endonuclease 3D structures]]
== References ==
== References ==
<references/>
<references/>
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[[Category: Bpt4]]
[[Category: Bpt4]]
[[Category: Crossover junction endodeoxyribonuclease]]
[[Category: Crossover junction endodeoxyribonuclease]]
[[Category: Large Structures]]
[[Category: Biertumpfel, C]]
[[Category: Biertumpfel, C]]
[[Category: Suck, D]]
[[Category: Suck, D]]