6me2: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==XFEL crystal structure of human melatonin receptor MT1 in complex with ramelteon== | |||
<StructureSection load='6me2' size='340' side='right'caption='[[6me2]], [[Resolution|resolution]] 2.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6me2]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ME2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ME2 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=JEV:N-{2-[(8S)-1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl]ethyl}propanamide'>JEV</scene>, <scene name='pdbligand=OLA:OLEIC+ACID'>OLA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | |||
[[Category: | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=YCM:S-(2-AMINO-2-OXOETHYL)-L-CYSTEINE'>YCM</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6me2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6me2 OCA], [http://pdbe.org/6me2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6me2 RCSB], [http://www.ebi.ac.uk/pdbsum/6me2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6me2 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/MTR1A_HUMAN MTR1A_HUMAN]] High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Batyuk, A]] | |||
[[Category: Brehm, W]] | |||
[[Category: Cherezov, V]] | |||
[[Category: Gati, C]] | |||
[[Category: Grandner, J M]] | |||
[[Category: Grant, T D]] | |||
[[Category: Han, G W]] | |||
[[Category: Ishchenko, A]] | |||
[[Category: Johansson, L C]] | |||
[[Category: Katritch, V]] | |||
[[Category: Liu, W]] | |||
[[Category: Madsen, C]] | |||
[[Category: McCorvy, J D]] | |||
[[Category: Michaelian, N]] | |||
[[Category: Olsen, R H.J]] | |||
[[Category: Patel, N]] | |||
[[Category: Roth, B L]] | |||
[[Category: Stauch, B]] | |||
[[Category: Tribo, A R]] | |||
[[Category: Weierstall, U]] | |||
[[Category: White, T A]] | |||
[[Category: Zhu, L]] | |||
[[Category: Circadian rhythm]] | |||
[[Category: Gpcr]] | |||
[[Category: Jetlag]] | |||
[[Category: Lcp]] | |||
[[Category: Membrane protein]] | |||
[[Category: Pg]] | |||
[[Category: Ramelteon]] | |||
[[Category: Xfel]] | |||
Revision as of 06:57, 24 April 2019
XFEL crystal structure of human melatonin receptor MT1 in complex with ramelteon
| ||||||||||||
