6mfs: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6mfs is ~~ON HOLD~~

==Mouse talin1 residues 1-138 fused to residues 169-400 in complex with phosphatidylinositol 4,5-bisphosphate (PIP2)==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[6mfs]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MFS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6MFS FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PIO:[(2R)-2-OCTANOYLOXY-3-[OXIDANYL-[(1R,2R,3S,4R,5R,6S)-2,3,6-TRIS(OXIDANYL)-4,5-DIPHOSPHONOOXY-CYCLOHEXYL]OXY-PHOSPHORYL]OXY-PROPYL]+OCTANOATE'>PIO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6mfs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mfs OCA], [http://pdbe.org/6mfs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6mfs RCSB], [http://www.ebi.ac.uk/pdbsum/6mfs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6mfs ProSAT]</span></td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/TLN1_MOUSE TLN1_MOUSE]] Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts.

__TOC__

</StructureSection>

[[Category: Chinthalapudi, K]]

[[Category: Izard, T]]

[[Category: Rangarajan, E S]]

[[Category: Angiogenesis]]

[[Category: Cell adhesion]]

[[Category: Integrin activation]]

[[Category: Phosphoinositide]]

[[Category: Phospholipid]]

[[Category: Talin activation]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6mfs is ON HOLD
+==Mouse talin1 residues 1-138 fused to residues 169-400 in complex with phosphatidylinositol 4,5-bisphosphate (PIP2)==
+<StructureSection load='6mfs' size='340' side='right' caption='[[6mfs]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6mfs]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MFS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6MFS FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PIO:[(2R)-2-OCTANOYLOXY-3-[OXIDANYL-[(1R,2R,3S,4R,5R,6S)-2,3,6-TRIS(OXIDANYL)-4,5-DIPHOSPHONOOXY-CYCLOHEXYL]OXY-PHOSPHORYL]OXY-PROPYL]+OCTANOATE'>PIO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6mfs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mfs OCA], [http://pdbe.org/6mfs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6mfs RCSB], [http://www.ebi.ac.uk/pdbsum/6mfs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6mfs ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/TLN1_MOUSE TLN1_MOUSE]] Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts.
+__TOC__
+</StructureSection>
+[[Category: Chinthalapudi, K]]
+[[Category: Izard, T]]
+[[Category: Rangarajan, E S]]
+[[Category: Angiogenesis]]
+[[Category: Cell adhesion]]
+[[Category: Integrin activation]]
+[[Category: Phosphoinositide]]
+[[Category: Phospholipid]]
+[[Category: Talin activation]]